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View Structure Prediction Details

Protein: en-PB, en-PA
Organism: Drosophila melanogaster
Length: 552 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for en-PB, en-PA.

Description E-value Query
Range
Subject
Range
gi|763443, gi|72258 - gi|763443|gb|AAA65478.1| engrailed protein, pir||WJFFEN homeotic protein engrailed - fruit fly (Dros...
170.0 [0..1] [552..1]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALEDRCSPQ SAPSPITLQM QHLHHQQQQQ QQQQQQMQHL HQLQQLQQLH QQQLAAGVFH  60
   61 HPAMAFDAAA AAAAAAAAAA AHAHAAALQQ RLSGSGSPAS CSTPASSTPL TIKEEESDSV 120
  121 IGDMSFHNQT HTTNEEEEAE EDDDIDVDVD DTSAGGRLPP PAHQQQSTAK PSLAFSISNI 180
  181 LSDRFGDVQK PGKSMENQAS IFRPFEASRS QTATPSAFTR VDLLEFSRQQ QAAAAAATAA 240
  241 MMLERANFLN CFNPAAYPR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [260-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHEEIVQSRL RRSAANAVIP PPMSSKMSDA NPEKSALGSL CKAVSQIGQP AAPTMTQPPL  60
   61 SSSASSLASP PPASNASTIS STSSVATSSS SSSSGCSSAA SSLNSSPSSR LGASGSGVNA 120
  121 SSPQPQPIPP PSAVSRDSGM ESSDDTRSET GSTTTEGGKN EMWPAWVYCT RYSDRPSSGP 180
  181 RYRRPKQPKD KTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [453-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEKRPRTAFS SEQLARLKRE FNENRYLTER RRQQLSSELG LNEAQIKIWF QNKRAKIKKS  60
   61 TGSKNPLALQ LMAQGLYNHT TVPLTKEEEE LEMRMNGQIP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.0
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.20953772435302 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle