YRC Public Data Repository - Protein Structure Prediction

Protein:	lin-3
Organism:	Caenorhabditis elegans
Length:	462 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-3.

Description	E-value	Query Range	Subject Range
lin-3 - lin-3 growth factor precursor status:Confirmed UniProt:Q03345 protein_id:CAD27623.1	854.0	[0..1]	[462..1]

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Predicted Domain #1

Region A:
Residues: [1-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKMLLFCIL LLFMPQFTES CLPSWFRQER SAPEQLQSAE NAAENSGSVP PDTSRNSLET  60
   61 NEIGDAPSST STPETPTETT ISEAGDDEKR TEEVAKELIE KEAEYEGEYE DEKVDEEVEE 120
  121 ALKYNEDATQ DATSTLKPAV RKEIEKLKEA KCKDYCHHNA TCHVEVIFRE DRVSAVVPSC 180
  181 HCPQGWEGTR CDRHYVQAFY APINGRYNGK TKKPLIFMVH H

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [222-462]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNQTISTTPS SQDSEISSIF SGLYERIVQS STSAIPAFAF LIVMLIMFIT IVVYAYRRMS  60
   61 KRSDDMTYTM SHMCPPEAFN VLKTPNGRHI PVHQIPSCSY TIPTPGTVPP NISSTPGSRI 120
  121 PTRQQAIRNN EQARNNFFSI LRSQGTIPSR SINDDDTPKH YKSVPRVEVS AINYSGHIDF 180
  181 STVSYQSTES EVSKASVTCP PPAHTVINIE LDSADTNFRS PSRSSGEQGS PATCEPMIRH 240
  241 T