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View Structure Prediction Details

Protein: MBD3_MOUSE
Organism: Mus musculus
Length: 285 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MBD3_MOUSE.

Description E-value Query
Range
Subject
Range
MBD3 - methyl-CpG binding domain protein 3
gi|55647849 - gi|55647849|ref|XP_512241.1| PREDICTED: methyl-CpG binding domain protein 3 isoform 2 [Pan troglodyt...
461.0 [0..1] [267..1]
gi|109122751 - gi|109122751|ref|XP_001095979.1| PREDICTED: similar to methyl-CpG binding domain protein 3 [Macaca m...
460.0 [0..1] [267..1]
gi|73987317, gi|... - gi|73987325|ref|XP_868594.1| PREDICTED: similar to methyl-CpG binding domain protein 3 isoform 5 [Ca...
454.0 [0..1] [267..1]
gi|47215634 - gi|47215634|emb|CAG01351.1| unnamed protein product [Tetraodon nigroviridis]
443.0 [0..1] [260..1]
gi|24210495 - gi|24210495|dbj|BAC22082.1| methyl-CpG binding protein MBD3 [Xenopus laevis]
443.0 [0..1] [262..1]
gi|37681869, gi|... - gi|47086507|ref|NP_997934.1| methyl-CpG binding domain protein 3a [Danio rerio], gi|37681869|gb|AAQ9...
441.0 [0..1] [270..1]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERKRWECPA LPQGWEREEV PRRSGLSAGH RDVFYYSPSG KKFRSKPQLA RYLGGSMDLS  60
   61 TFDFRTGKML MNKMNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1d9nA
Description: Methylation-dependent transcriptional repressor MBD1/PCM1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [77-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRQRVRYDSS NQVKGKPDLN TALPVRQTAS IFKQPVTKIT NHPSNKVKSD PQKAVDQPRQ  60
   61 LFWEKKLSGL SAFDIAEELV RTMDLPKGLQ GVGPGCTDET LLSAIASALH TSTLPITGQL 120
  121 SAAVEKNPGV WLNTAQPLC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [216-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAFMVTDDDI RKQEELVQQV RKRLEEALMA DMLAHVEELA RDGEAPLDKA CAEEEEEEEE  60
   61 EEEEPEPERV 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle