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View Structure Prediction Details

Protein: MTAP_MOUSE
Organism: Mus musculus
Length: 283 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTAP_MOUSE.

Description E-value Query
Range
Subject
Range
gi|114623942 - gi|114623942|ref|XP_001153022.1| PREDICTED: similar to Chain A, Structure Of Human 5-Deoxy-5-Methylt...
MTAP - methylthioadenosine phosphorylase
MTAP_MACMU - S-methyl-5'-thioadenosine phosphorylase OS=Macaca mulatta GN=MTAP PE=3 SV=1
CCDS6509.1_1 - null
328.0 [0..1] [283..1]
gi|114623940 - gi|114623940|ref|XP_001152954.1| PREDICTED: similar to Chain A, Structure Of Human 5-Deoxy-5-Methylt...
319.0 [0..1] [283..1]
gi|73971706 - gi|73971706|ref|XP_531959.2| PREDICTED: similar to S-methyl-5-thioadenosine phosphorylase (5-methylt...
316.0 [0..12] [283..95]
MTAP_DANRE - S-methyl-5'-thioadenosine phosphorylase OS=Danio rerio GN=mtap PE=2 SV=2
310.0 [0..5] [283..2]
gi|58332838, gi|... - gi|58332838|ref|NP_001011495.1| 5'-methylthioadenosine phosphorylase [Xenopus (Silurana) tropicalis]...
295.0 [0..6] [283..3]

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Predicted Domain #1
Region A:
Residues: [1-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASGSACTAV KIGIIGGTGL DDPEILEGRT EKYVDTPFGK PSDALILGKI KNVDCVLLAR  60
   61 HGRQHTIMPS KVNYQANIWA LKEEGCTHVI VTTACGSLRE EIQPGDMVII DQFIDRTSLR 120
  121 PQTFYDGSHC SARGVCHIPM AEPFCPKTRE VLIETAKKLG LRCHSKGTIV TIEGPRFSSR 180
  181 AESLIFRTWG ADVVNMTTVP EVVLAKEAGI CYASIAMATD YDCWKEHEEA VSVDGVLKTM 240
  241 KENANKAKSL LLTTIPQIGS MEWSETLRNL KNMAQFSVLP PRH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.09691
Match: 1cb0A
Description: 5'-deoxy-5'-methylthioadenosine phosphorylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-methyl-5-thioadenosine phosphorylase activity 3.89303327575747 bayes_pls_golite062009
purine-nucleoside phosphorylase activity 3.68206997938506 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.66765825367784 bayes_pls_golite062009
transferase activity 2.89508986830218 bayes_pls_golite062009
catalytic activity 2.18268586151113 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.01261001022129 bayes_pls_golite062009
nucleoside binding 1.11256863177576 bayes_pls_golite062009
purine binding 1.00226077276304 bayes_pls_golite062009
nucleobase binding 0.914372836742171 bayes_pls_golite062009
protein binding 0.295595362082672 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 0.0636156969949176 bayes_pls_golite062009

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