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View Structure Prediction Details

Protein: asm-3
Organism: Caenorhabditis elegans
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asm-3.

Description E-value Query
Range
Subject
Range
asm-3 - sphingomyelin phosphodiesterase status:Partially_confirmed UniProt:Q9UAY4 protein_id:AAD14755.2
473.0 [0..1] [545..45]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIAVFICET FHIEDNDVCN FIISDFSDEF MYVIKQILVT PHQLCGLLMK NDCGDFVDPL  60
   61 ATIWNMTIPG NQPPFVPKQV VPP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNPTLRALHL TDLHVDMFYT VGLEADCGTP QCCRPQDMNV EIVENGDVKQ PAGPWGSVGS  60
   61 CDTPYWLLTN MLQNIASTAG KLDYIMVSGD LVSHTVWAYT PETHSFMVKN LSDTIRSYFP 120
  121 KTPVYFAVGN HEGVPVDNIA PHFTPKKYHM DWLYKAMSNA WQGWIPADQE KSLEYNGCYM 180
  181 KKIYDGLRMI SLNNVYGDRI NFWLYINQTD PDGTLQWLIN QLQDAENVGD KVHIVAHIPG 240
  241 SDGEALEGYA LNYYKIINRY ANTVVGQFFG HTHSEKFYMM YANPDDYKST PTNVVYSAPS 300
  301 VTPYSDYFPA YRIYTIDGVH KGSTYQVIDY EEWFFNLTSN NANPTNVKWE VLYQSANMEY 360
  361 GLKGQIPTEY NQMIERMKTD DSLFNKYYEN HNRRSIYDGR APCNDQQCRN GYLCDARQFH 420
  421 QTQQLCTDLE GGIQKPEPKK NKYSARFATS NERRRGKEEC KI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 1kbpA
Description: Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoric ester hydrolase activity 3.05960970003903 bayes_pls_golite062009
hydrolase activity 2.06280293513737 bayes_pls_golite062009
catalytic activity 1.39852585255405 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.04077570202244 bayes_pls_golite062009
phosphatase activity 0.76188635342041 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.744264552706022 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.631630849060451 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle