YRC Public Data Repository - Protein Structure Prediction

Protein:	HTD2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HTD2_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|91777550, gi\|... - gi\|91777550\|ref\|YP_552758.1\| hypothetical protein Bxe_B2585 [Burkholderia xenovorans LB400], gi\|9169...	239.0	[0..1]	[294..12]
gi\|134137228, gi... - gi\|67545946\|ref\|ZP_00423864.1\| conserved hypothetical protein [Burkholderia vietnamiensis G4], gi\|67...	235.0	[0..1]	[280..13]
gi\|72120710, gi\|... - gi\|73537373\|ref\|YP_297740.1\| hypothetical protein Reut_B3538 [Ralstonia eutropha JMP134], gi\|7212071...	235.0	[0..1]	[273..14]
gi\|46315875, gi\|... - gi\|78060833\|ref\|YP_367408.1\| hypothetical protein Bcep18194_C7720 [Burkholderia sp. 383], gi\|7796538...	233.0	[0..1]	[285..18]
gi\|145589423, gi... - gi\|145589423\|ref\|YP_001156020.1\| hypothetical protein Pnuc_1241 [Polynucleobacter necessarius subsp....	232.0	[0..1]	[284..18]
gi\|93356677, gi\|... - gi\|94312825\|ref\|YP_586034.1\| hypothetical protein Rmet_3897 [Ralstonia metallidurans CH34], gi\|93356... gi\|222872792, gi... - gi\|224163456\|ref\|XP_002338561.1\| predicted protein [Populus trichocarpa], gi\|222872792\|gb\|EEF09923.1...	230.0	[0..1]	[277..13]
gi\|84352304 - gi\|84352304\|ref\|ZP_00977271.1\| COG3777: Uncharacterized conserved protein [Burkholderia cenocepacia ...	229.0	[0..1]	[294..18]
gi\|105897719, gi... - gi\|67656673\|ref\|ZP_00454055.1\| conserved hypothetical protein [Burkholderia cenocepacia AU 1054], gi... gi\|67102562, gi\|... - gi\|67663793\|ref\|ZP_00461072.1\| conserved hypothetical protein [Burkholderia cenocepacia HI2424], gi\|...	226.0	[0..1]	[285..18]
gi\|33567208, gi\|... - gi\|33599612\|ref\|NP_887172.1\| hypothetical protein BB0622 [Bordetella bronchiseptica RB50], gi\|335672...	223.0	[0..1]	[291..13]
gi\|33595317 - gi\|33595317\|ref\|NP_882960.1\| hypothetical protein BPP0616 [Bordetella parapertussis 12822] gi\|33565394 - gi\|33565394\|emb\|CAE36201.1\| conserved hypothetical protein [Bordetella parapertussis]	222.0	[0..1]	[291..13]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKVVLKDF LSQAPIDKLK ATLSGHLPVS CITMDAKITS LQPGYHFLFF SLASPESNLN  60
   61 SDGYESLYSP KPNNPFSFKR RIWLHGVLRF HRPLHLFQTS ECHELIQEES VKSPSITKEV 120
  121 EACLPKSSFL TKPTSEKQTK HVYIRRKIYD SQHQLCIEED RTLAYLNRQE LAIPKTLRSK 180
  181 SIPQHSWVFT PTPIMVFRYS ALMFNAHMIH WNATYATKSE NYPNLVLPGP LLVTSMLEYF 240
  241 RSVYPQMSKN MKRFEFRLLS PAFVNQPLRI CISETGNLWI DRFTTDLDPP SLIARGRVYT 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.30103
Match:	1s9cA
Description:	Crystal structure analysis of the 2-enoyl-CoA hydratase 2 domain of human peroxisomal multifunctional enzyme type 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	2.3187640589669	bayes_pls_golite062009
thiolester hydrolase activity	1.14125301545576	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.900771387775228	bayes_pls_golite062009
catalytic activity	0.74605540351792	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: