YRC Public Data Repository - Protein Structure Prediction

Protein:	DOPP1_MOUSE
Organism:	Mus musculus
Length:	238 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOPP1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|62644867, gi\|... - gi\|62644867\|ref\|XP_231129.3\| PREDICTED: similar to Dolichyldiphosphatase 1 (Dolichyl pyrophosphate p...	389.0	[0..1]	[238..1]
DOLPP1 - dolichyl pyrophosphate phosphatase 1 gi\|114627090 - gi\|114627090\|ref\|XP_520304.2\| PREDICTED: dolichyl pyrophosphate phosphatase 1 isoform 2 [Pan troglod...	387.0	[0..1]	[238..1]
gi\|20072969 - gi\|20072969\|gb\|AAH26544.1\| Dolichyl pyrophosphate phosphatase 1 [Mus musculus]	387.0	[0..1]	[238..1]
gi\|73967810 - gi\|73967810\|ref\|XP_850246.1\| PREDICTED: similar to Dolichyldiphosphatase 1 (Dolichyl pyrophosphate p...	383.0	[0..1]	[238..1]
gi\|76630766 - gi\|76630766\|ref\|XP_581102.2\| PREDICTED: dolichyl pyrophosphate phosphatase 1 isoform 1 [Bos taurus]	382.0	[0..1]	[238..1]
gi\|89269908, gi\|... - gi\|89269908\|emb\|CAJ82482.1\| dolichyl pyrophosphate phosphatase 1 [Xenopus tropicalis], gi\|62860144\|r...	345.0	[0..1]	[238..1]
gi\|54035387, gi\|... - gi\|55742543\|ref\|NP_001007062.1\| dolichyl pyrophosphate phosphatase 1 [Danio rerio], gi\|54035387\|gb\|A... gi\|55742543 - ref\|NP_001007062.1\| zgc:101585 [Danio rerio]	327.0	[0..1]	[238..1]
gi\|114627092 - gi\|114627092\|ref\|XP_001162767.1\| PREDICTED: similar to dolichyl pyrophosphate phosphatase CWH8 isofo... gi\|194374377, gi... - gi\|209571523\|ref\|NP_001129389.1\| dolichyl pyrophosphate phosphatase 1 isoform b [Homo sapiens], gi\|1...	307.0	[0..1]	[238..1]

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Predicted Domain #1

Region A:
Residues: [1-238]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAADGQCSLP ASWRPVTLTH VEYPAGDLSG HLLAYLSLSP IFVVVGFLTL IIFKRELHTI  60
   61 SFLGGLALNQ GVNWLIKHVI QEPRPCGGPH TAVGTKYGMP SSHSQFMWFF SVYSFLFLYL 120
  121 RMHQTNNARF LDLLWRHVLS LGLLTAAFLV SYSRVYLLYH TWSQVFYGGV AGSLMAVAWF 180
  181 IITQEILTPL FPRIAAWPIS EFFLIRDTSL IPNVLWFEYT VTRAEARNRQ RKLGTKLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.25
Match:	1d2tA
Description:	Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.732568437339568	bayes_pls_golite062009
phosphatase activity	0.451712594933962	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.280035971145935	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: