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View Structure Prediction Details

Protein: gi|109066782
Organism: Macaca mulatta
Length: 147 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|109066782.

Description E-value Query
Range
Subject
Range
gi|37590333, gi|... - gi|41152425|ref|NP_955958.1| ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) [Danio rerio...
1.0E-54 [1..147] [1..147]
gi|116487484, gi... - gi|118404876|ref|NP_001072891.1| ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog) [Xenopus (Silur...
gi|54311502, gi|... - gi|54311502|gb|AAH84849.1| LOC495381 protein [Xenopus laevis], gi|49899030|gb|AAH76728.1| Ube2d2-pro...
2.0E-54 [1..147] [1..147]
gi|62738886 - gi|62738886|pdb|1Z2U|A Chain A, The 1.1a Crystallographic Structure Of Ubiquitin- Conjugating Enzyme...
3.0E-54 [1..147] [4..150]
gi|87239726 - gi|87239726|emb|CAJ57642.1| putative ubiquitin conjugating enzyme 2 [Oesophagostomum dentatum]
6.0E-54 [1..147] [1..147]
gi|83754950 - gi|83754950|pdb|2ESQ|A Chain A, Human Ubiquitin-Conjugating Enzyme (E2) Ubch5b Mutant Ser94gly
7.0E-54 [1..147] [3..149]
gi|48095652, gi|... - ref|XP_392337.1| similar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiqu...
8.0E-54 [1..147] [1..147]
gi|60653681, gi|... - gi|60653681|gb|AAX29534.1| ubiquitin-conjugating enzyme E2D 1 [synthetic construct], gi|30584383|gb|...
9.0E-54 [1..147] [1..147]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALKRIQKEL TDLQRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY  60
   61 PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120
  121 PEIAHTYKAD REKYNRLARE WTQKYAM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 1z2uA
Description: The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 11.3486134076304 bayes_pls_golite062009
small conjugating protein ligase activity 11.2964721480824 bayes_pls_golite062009
acid-amino acid ligase activity 10.2401422444624 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 8.93602533934698 bayes_pls_golite062009
HLH domain binding 8.10904818707269 bayes_pls_golite062009
ligase activity 5.17219147802758 bayes_pls_golite062009
SUMO ligase activity 3.88357560284404 bayes_pls_golite062009
ISG15 ligase activity 3.37361650623694 bayes_pls_golite062009
transcription regulator activity 2.21355731489173 bayes_pls_golite062009
nucleic acid binding 2.13970605403492 bayes_pls_golite062009
DNA binding 1.95596447916631 bayes_pls_golite062009
protein binding 1.77678273247394 bayes_pls_golite062009
binding 1.75350658654805 bayes_pls_golite062009
transcription repressor activity 1.5236035191291 bayes_pls_golite062009
transcription activator activity 1.19240180311941 bayes_pls_golite062009
catalytic activity 0.891402822028799 bayes_pls_golite062009
NEDD8 ligase activity 0.715654744941217 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.58835335751383 bayes_pls_golite062009
kinase activity 0.519703305315987 bayes_pls_golite062009
protein kinase activity 0.443948654247666 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.373779304908933 bayes_pls_golite062009
protein serine/threonine kinase activity 0.182854082413338 bayes_pls_golite062009
transcription corepressor activity 0.122859425935324 bayes_pls_golite062009
transferase activity 0.0984525836903841 bayes_pls_golite062009
transcription factor binding 0.0104967529560147 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle