YRC Public Data Repository - Protein Structure Prediction

Protein:	COAA_YERPA
Organism:	Yersinia pestis Antiqua
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COAA_YERPA.

Description	E-value	Query Range	Subject Range
COAA_PHOLL - Pantothenate kinase OS=Photorhabdus luminescens subsp. laumondii GN=coaA PE=3 SV=1 COAA_PHOLL - Pantothenate kinase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT...	9.0E-97	[1..316]	[1..316]
gi\|197239852, gi... - gi\|197266062\|ref\|ZP_03166135.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Sai... gi\|62182597, gi\|... - gi\|62182597\|ref\|YP_219014.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Choler...	3.0E-95	[1..316]	[3..318]
gi\|24054556, gi\|... - ref\|NP_709774.1\| rts gene product [Shigella flexneri 2a str. 301], gb\|AAN45481.1\| rts gene product ... gi\|110807829, gi... - gi\|110807829\|ref\|YP_691349.1\| pantothenate kinase [Shigella flexneri 5 str. 8401], gi\|110617377\|gb\|A...	3.0E-95	[1..316]	[53..368]
gi\|238794969, gi... - gi\|77976220\|ref\|ZP_00831732.1\| COG1072: Panthothenate kinase [Yersinia intermedia ATCC 29909], gi\|23...	3.0E-95	[1..316]	[1..316]
COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 gi\|213999715 - gi\|213999715\|ref\|ZP_03410450.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... COAA_SALA4 - Pantothenate kinase OS=Salmonella agona (strain SL483) GN=coaA PE=3 SV=1 COAA_SALPK - Pantothenate kinase OS=Salmonella paratyphi A (strain AKU_12601) GN=coaA PE=3 SV=1 gi\|205360640, gi... - gi\|205360640\|ref\|ZP_02684926.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Had... gi\|213163738 - gi\|213163738\|ref\|ZP_03349448.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typ... gi\|168468124, gi... - gi\|195628796\|gb\|EDX48226.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Newport... COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A GN=coaA PE=3 SV=1 COAA_SALNS - Pantothenate kinase OS=Salmonella newport (strain SL254) GN=coaA PE=3 SV=1 COAA_SALSV - Pantothenate kinase OS=Salmonella schwarzengrund (strain CVM19633) GN=coaA PE=3 SV=1 gi\|16762309 - gi\|16762309\|ref\|NP_457926.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ... COAA_SALTI - Pantothenate kinase OS=Salmonella typhi GN=coaA PE=3 SV=1 COAA_SALPA - Pantothenate kinase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=coaA PE=3 SV=1 gi\|29139432, gi\|... - gi\|29143797\|ref\|NP_807139.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Typhi ...	3.0E-95	[1..316]	[1..316]
gi\|227837533, gi... - gi\|227885495\|ref\|ZP_04003300.1\| pantothenate kinase [Escherichia coli 83972], gi\|227837533\|gb\|EEJ479... gi\|110644314, gi... - gi\|110644314\|ref\|YP_672044.1\| pantothenate kinase [Escherichia coli 536], gi\|110345906\|gb\|ABG72143.1... gi\|26250747, gi\|... - gi\|26250747\|ref\|NP_756787.1\| pantothenate kinase [Escherichia coli CFT073], gi\|26111178\|gb\|AAN83361.... gi\|115515367, gi... - gi\|117626243\|ref\|YP_859566.1\| pantothenate kinase [Escherichia coli APEC O1], gi\|115515367\|gb\|ABJ034... gi\|91074354, gi\|... - gi\|91212780\|ref\|YP_542766.1\| pantothenate kinase [Escherichia coli UTI89], gi\|91074354\|gb\|ABE09235.1... gi\|124497994, gi... - gi\|124532579\|ref\|ZP_01702258.1\| pantothenate kinase [Escherichia coli B], gi\|124497994\|gb\|EAY45534.1...	3.0E-95	[1..316]	[8..323]
COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=coaA PE=3 SV=... COAA_SALPC - Pantothenate kinase OS=Salmonella paratyphi C (strain RKS4594) GN=coaA PE=3 SV=1 COAA_SALTY - Pantothenate kinase OS=Salmonella typhimurium GN=coaA PE=3 SV=1 gi\|205321453, gi... - gi\|205357489\|ref\|ZP_02348072.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Sai... gi\|205326991, gi... - gi\|205358199\|ref\|ZP_02576422.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar 4,[... gi\|205335977, gi... - gi\|205359466\|ref\|ZP_02670230.2\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Hei... COAA_SALEP - Pantothenate kinase OS=Salmonella enteritidis PT4 (strain P125109) GN=coaA PE=3 SV=1 COAA_SALHS - Pantothenate kinase OS=Salmonella heidelberg (strain SL476) GN=coaA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=coaA] [protein=pantothenate kinase] [protein_id=YP_005240422.1] [location=complement(4372275..... gi\|194458277, gi... - gi\|194471913\|ref\|ZP_03077897.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Ken... COAA_SALDC - Pantothenate kinase OS=Salmonella dublin (strain CT_02021853) GN=coaA PE=3 SV=1 gi\|200388743, gi... - gi\|200388743\|ref\|ZP_03215355.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Vir... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis (strain SC-B67) GN=coaA PE=3 SV=2 COAA_SALPB - Pantothenate kinase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=coaA PE=3 SV=1 COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2 gi\|205340453, gi... - gi\|205340453\|gb\|EDZ27217.1\| pantothenate kinase [Salmonella enterica subsp. enterica serovar Weltevr... COAA_SALCH - Pantothenate kinase OS=Salmonella choleraesuis GN=coaA PE=3 SV=2	4.0E-95	[1..316]	[1..316]
COAA_HAEDU - Pantothenate kinase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=coaA PE=3 SV=1 COAA_HAEDU - Pantothenate kinase OS=Haemophilus ducreyi GN=coaA PE=3 SV=1	4.0E-95	[1..316]	[1..316]
gi\|226903057, gi... - gi\|237702744\|ref\|ZP_04533225.1\| pantothenate kinase [Escherichia sp. 3_2_53FAA], gi\|226903057\|gb\|EEH... gi\|254039233, gi... - gi\|254039233\|ref\|ZP_04873282.1\| pantothenate kinase [Escherichia sp. 1_1_43], gi\|226838468\|gb\|EEH704... gi\|147780 - gi\|147780\|gb\|AAA76838.1\| rts [Escherichia coli]	4.0E-95	[1..316]	[21..336]
gi\|238712695, gi... - gi\|77956141\|ref\|ZP_00820277.1\| COG1072: Panthothenate kinase [Yersinia bercovieri ATCC 43970], gi\|23...	5.0E-95	[1..316]	[1..316]

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Predicted Domain #1

Region A:
Residues: [1-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKREQSLAT PYLQFDRTQW AALRDSVPLT LTEEEIVKLK GINEDLSLDE VAQIYLPLSR  60
   61 LLNFYISSNL RRQAVLEQFL GTDGQRIPYV IGIAGSVAVG KSTTARLLQA LLSRWPEHRS 120
  121 VELITTDGFL HPNKVLNERG LMKKKGFPES YDMHNLVKFV SEVKSGADYV TAPVYSHLIY 180
  181 DVVPDGNKVI KQPDILILEG LNVLQSGMDY PHDPHHVFVS DFVDFSIYVD APEDLLQSWY 240
  241 INRFLKFRQG AFSNPDSYFH NYAKLPETEA IKIATQLWNE INGLNLKQNI LPTRERASLI 300
  301 MTKSANHAVE SVRLRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.39794
Match:	1esmA
Description:	Pantothenate kinase PanK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
dephospho-CoA kinase activity	0.747335572592521	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: