YRC Public Data Repository - Protein Structure Prediction

Protein:	YBCY_ECOLI
Organism:	Escherichia coli
Length:	194 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBCY_ECOLI.

Description	E-value	Query Range	Subject Range
UBIE_SHELP - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella loihica (strain ATCC BAA-...	151.0	[0..1]	[191..43]
gi\|149746384, gi... - gi\|153840045\|ref\|ZP_01992712.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Vibrio p... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio parahaemolyticus serotype O3:... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio parahaemolyticus GN=ubiE PE=3 S...	150.0	[0..1]	[192..51]
gi\|194537307, gi... - gi\|75820016\|ref\|ZP_00750074.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...	149.0	[0..1]	[191..52]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	149.0	[0..1]	[192..56]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	149.0	[0..1]	[191..52]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	149.0	[0..1]	[192..56]
UBIE_SHEDO - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella denitrificans (strain OS2...	149.0	[0..1]	[191..43]
gi\|91224931, gi\|... - gi\|91224931\|ref\|ZP_01260190.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio alginol...	149.0	[0..1]	[192..51]
UBIE_SHESM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella sp. (strain MR-4) GN=ubiE... UBIE_SHESA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella sp. (strain ANA-3) GN=ubi... UBIE_SHESR - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella sp. (strain MR-7) GN=ubiE...	149.0	[0..1]	[191..43]
UBIE_SHESW - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella sp. (strain W3-18-1) GN=u... UBIE_SHEPC - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Shewanella putrefaciens (strain CN-3... gi\|124507974, gi... - gi\|124549254\|ref\|ZP_01707584.1\| ubiquinone/menaquinone biosynthesis methyltransferases [Shewanella p...	148.0	[0..1]	[191..43]

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Predicted Domain #1

Region A:
Residues: [1-194]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVSNRLAWG CPTKEHLLPH FLEHLGNNHL DIGVGTGFYL THVPESSLIS LMDLNEASLN  60
   61 AASTRAGESK IKHKISHDVF EPYPAALHGQ FDSISMSYLL HCLPGNISTK SCVIRNAAQA 120
  121 LTDDGTLYGA TILGDGVVHN SFGQKLMRIY NQKGIFSNTK DSEEGLTHIL SEHFENVKTK 180
  181 VQGTVVMFSA SGKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.522879
Match:	1vl5A
Description:	Crystal structure of hypothetical protein (BH2331) from Bacillus halodurans at 1.95 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.723277178398499	bayes_pls_golite062009
transferase activity	0.64512166557639	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.54403439349476	bayes_pls_golite062009
methyltransferase activity	0.54389223881989	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: