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View Structure Prediction Details

Protein: CG5621-PB
Organism: Drosophila melanogaster
Length: 956 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5621-PB.

Description E-value Query
Range
Subject
Range
GRIK2_MOUSE, GLK... - (P39087) Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) ...
574.0 [0..1] [866..1]

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Predicted Domain #1
Region A:
Residues: [1-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWFVKMISTE ASFPLGFILT SLLLAFPGCR GERTNVGLVY ENTDPDLEKI FHLAISKANE  60
   61 ENEDLQLHGV SVSIEPGNSF ETSKKLCKML RQNLVAVFGP TSNLAARHAM SICDAKELPF 120
  121 LDTRWDFGAQ LPTINLHPHP ATLGVALRDM VVALGWESFT IIYESGEYLP TVRELLQMYG 180
  181 TAGPTVTVRR YELDLNGNYR NVLRRIRNAD DFSFVVVGSM ATLPEFFKQA QQVGLVTSDY 240
  241 RYIIGNLDWH TMDLEPYQHA GTNITGLRLV SPDSEQVQEV AKALYESEEP FQNVSCPLTN 300
  301 SMALVYDGVQ LLAETYKHVN FRPVALSCND DSAWDKGYTL VNYMKSLTLN GLTGPIRFDY 360
  361 EGLRTDFKLE VIELAVSGMQ KIGQWSGEDG FQENRPAPAH SLEPDMRSLV NKSFVVITAI 420
  421 SEPYGMLKET SEKLEGNDQF EGFGIELIDE LSKKLGFSYT WRLQED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.522879
Match: 2e4uA
Description: No description for 2e4uA was found.

Predicted Domain #2
Region A:
Residues: [467-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKYGGIDPKT GEWNGMLREI IDSRADMGIT DLTMTSERES GVDFTIPFMS LGIGILFRKP  60
   61 MKEPPKLFSF MSPFSGEVWL WLGLAYMGVS ISMFVLGRLS PAEWDNPYPC IEEPT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.06
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [582-842]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELENQFSFAN CLWFSIGALL QQGSELAPKA YSTRAVAASW WFFTLILVSS YTANLAAFLT  60
   61 VESLVTPIND ADDLSKNKGG VNYGAKIGGA TFNFFKESNY PTYQRMYEFM RDNPQYMTNT 120
  121 NQEGVDRVEN SNYAFLMEST TIEYITERRC TLTQVGALLD EKGYGIAMRK NWPYRDTLSQ 180
  181 AVLEMQEQGL LTKMKTKWWQ EKRGGGACSD ADEDSGAVAL EISNLGGVFL VMGVGSFFGI 240
  241 FVSLLEMVLG VKERSDENQE A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.522879
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [843-956]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSDASSLGF ANLGGVYLVM FVGSCFGSIY GLVNCVVSVY LRARENKVSF KTELLDEIRF  60
   61 ILQCSGNTKA VKYPKNSSRS NASSKSKGSS MSVDSLPEDT SEADASGKHN HGKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle