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View Structure Prediction Details

Protein: GluRIIE-PB
Organism: Drosophila melanogaster
Length: 897 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GluRIIE-PB.

Description E-value Query
Range
Subject
Range
GRIK2_MOUSE, GLK... - (P39087) Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) ...
553.0 [0..1] [875..12]

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Predicted Domain #1
Region A:
Residues: [1-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFFNHFVILW SLFSIHISVN WAQYENFGGY DNYQSLESVP IGLLTDQNTE QMNIVFDHAI  60
   61 DVANQEVGTS LTSLKEEVNY GDAYQSYGKL CRMLETGIAG VFGPSSRHTA VHLMSICDAM 120
  121 DIPHIYSYMS ENAEGFNLHP HPADLAKALY SLITEFNWTR FIFLYESAEY LNILNELTTM 180
  181 LGKSGTVITV LRYDMQLNGN YKQVLRRVRK SVDNRIVVVG SSETMPEFLN QAQQVGIINE 240
  241 DYKYIIGNLD FHSFDLEEYK YSEANITGLR LFSPEKMAVK ELLMKLGYPT DQDEFRNGSC 300
  301 PITVEMALTY DAVQLFAQTL KNLPFKPMPQ NCSQRTESVR DDGSSFKNYM RTLRLTDRLL 360
  361 TGPIYFEGNV RKGYHLDVIE LQPSGIVKVG TWDEDRQYRP QRLAPTTAQF DSVDNSLANK 420
  421 TFIILLSVPN KPYAQLVETY KQLEGNSQYE GYGVDLIKEL ADKLGFNFTF VNGGNDYGSY 480
  481 NKSTNESTGM LREIMT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 2e4uA
Description: No description for 2e4uA was found.

Predicted Domain #2
Region A:
Residues: [497-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRADLAITDL TITSEREQAL DFTIPFMNLG IAILYLKPQK ATPELFTFMD PFSEEVWWFL  60
   61 GFSFLGVSLS FFILGRLSPS EWDNPYPCI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.33
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [586-798]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEPEELENQF TLGNSIWFTT GALLQQGSEI GPKALSTRTV ASFWWFFTLI VVSSYTANLA  60
   61 AFLTIEKPQS LINSVDDLAD NKDGVVYGAK KTGSTRNFFM TSAEERYKKM NKFMSENPQY 120
  121 LTEDNMEGVN RVKTNTHYAF LMESTSIEYN TKRECNLKKI GDALDEKGYG IAMRKDWPHR 180
  181 GKFNNALLEL QEQGVLEKMK NKWWNEVGTG ICA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.39794
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [799-897]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKEDAPDATP LDMNNLEGVF FVLLVGSCCA LLYGIISWVL FVMKKAHHYR VPLRDALKEE  60
   61 FQFVIDFNNY VRVLKNSASI YSRSRQSSMS VASVAQESQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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