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View Structure Prediction Details

Protein: FBpp0292488
Organism: Drosophila melanogaster
Length: 608 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0292488.

Description E-value Query
Range
Subject
Range
gi|109464704 - gi|109464704|ref|XP_342224.2| PREDICTED: similar to Protein kinase C iota type (nPKC-iota) (Atypical...
537.0 [0..2] [608..300]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKMPSQILN DGSSVSLNSA SMNMANTPNS ITVKTAYNGQ IIITTINKNI SYEELCYEIR  60
   61 NICRFPLDQP FTIKWVDEEN DPCTISTKME LDEAIRLYEM NFDSQLVIHV FPNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 1vd2A
Description: Solution Structure of the PB1 domain of PKCiota
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.178906437366734 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [115-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQAPGLSCDG EDRSIYRRGA RRWRKLYRVN GHIFQAKRFN RRAFCAYCQD RIWGLGRQGF  60
   61 KCIQCKLLVH KKCHKLVQKH CTDQPEPLVK ERAEESSDPI PVPLPPLPYE AMSGGAEACE 120
  121 THDHAHIVAP PPPEDPLEPG TQRQYSLNDF ELIRVIGRGS YAKVLMVELR RTRRIYAMKV 180
  181 IKKALVTDDE DIDWVQTEKH VFETASNHPF LVGLHSCFQT PSRLFFVIEF VRGGDLMYHM 240
  241 QRQRRLPEEH ARFYAAEISL ALNFLHEKGI IYRDLKLDNV LLDHEGHIKL TDYGMCKEGI 300
  301 RPGDTTSTFC GTPNYIAPEI LRGEDYGFSV DWWALGVLLY EMLAGRSPFD LAGASENPDQ 360
  361 NTEDYLFQVI LEKTIRIPRS LSVRAASVLK GFLNKNPADR LGCHRESAFM DIVSHPFFKN 420
  421 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.045757
Match: 2ptkA
Description: CHICKEN SRC TYROSINE KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [535-608]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDWELIAQKE VQPPYIPNID TGDPYVTSNF DVQFTQEPAV LTPDDPHVID NIDQSEFEGF  60
   61 EYVNPLLMSL EDCV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.522879
Match: 1zrzA
Description: Crystal Structure of the Catalytic Domain of Atypical Protein Kinase C-iota
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle