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View Structure Prediction Details

Protein: p120ctn-PB
Organism: Drosophila melanogaster
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for p120ctn-PB.

Description E-value Query
Range
Subject
Range
p120ctn-PA - The gene Adherens junction protein p120 is referred to in FlyBase by the symbol Dmel\p120ctn (CG1748...
512.0 [0..1] [767..15]

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Predicted Domain #1
Region A:
Residues: [1-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTHINMDL SLTHEPANMQ SQFGSFQNYD QFSAAGYSST PLYITKPTGV GAITKVAPHC  60
   61 SQNKIETNST DNSIPDIENH PLATTVRYVQ AGQYEDTSEY GVAGLTCGID SEYTAEAVVP 120
  121 YCYTSDANYT GIQNTTSSIK PFSGRPFNDN INGAEAVADS QCRTFKSSAE FKLPQFAMSS 180
  181 INTVPQRLEE KDDYIEGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.0
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [199-703]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENDICSTMRW RDPNLSEVIS FLSNPSSAIK ANAAAYLQHL CYMDDPNKQR TRSLGGIPPL  60
   61 VRLLSYDSPE IHKNACGALR NLSYGRQNDE NKRGIKNAGG IAALVHLLCR SQETEVKELV 120
  121 TGVLWNMSSC EDLKRSIIDE ALVAVVCSVI KPHSGWDAVC CGETCFSTVF RNASGVLRNV 180
  181 SSAGEHARGC LRNCEHLVEC LLYVVRTSIE KNNIGNKTVE NCVCILRNLS YRCQEVDDPN 240
  241 YDKHPFITPE RVIPSSSKGE NLGCFGTNKK KKEANNSDAL NEYNISADYS KSSVTYNKLN 300
  301 KGYEQLWQPE VVQYYLSLLQ SCSNPETLEA AAGAIQNLSA CYWQPSIDIR ATVRKEKGLP 360
  361 ILVELLRMEV DRVVCAVATA LRNLAIDQRN KELIGKYAMR DLVQKLPSGN VQHDQNTSDD 420
  421 TITAVLATIN EVIKKNPEFS RSLLDSGGID RLMNITKRKE KYTSCVLKFA SQVLYTMWQH 480
  481 NELRDVYKKN GWKEQDFVSK HFTAH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.221849
Match: 1xm9A
Description: Structure of the armadillo repeat domain of plakophilin 1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [704-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTPPSSPNNV NNTLNRPMAS QGRTRYEDRT IQRGTSTLYS ANDSSGAVMS NESAMLSEMV  60
   61 RKQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle