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View Structure Prediction Details

Protein: HXC5_MOUSE
Organism: Mus musculus
Length: 222 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXC5_MOUSE.

Description E-value Query
Range
Subject
Range
gi|73996360 - gi|73996360|ref|XP_849475.1| PREDICTED: similar to homeo box C5 [Canis familiaris]
153.0 [0..1] [222..1]
HGNC:5127|MIM:14... - C5
gi|146327466, gi... - gi|208966502|dbj|BAG73265.1| homeobox C5 [synthetic construct], gi|147897703|gb|AAI40273.1| Homeobox...
HOXC5 - homeobox C5
153.0 [0..1] [222..1]
HXC5_MOUSE - (P32043) Homeobox protein Hox-C5 (Hox-3.4) (Hox-6.2)
152.0 [0..1] [222..1]
gi|4322076 - gi|4322076|gb|AAD15947.1| homeobox protein [Danio rerio]
151.0 [0..1] [220..1]
gi|109483025 - gi|109483025|ref|XP_001068679.1| PREDICTED: similar to homeobox C5 [Rattus norvegicus]
150.0 [0..1] [220..1]
gi|154425967, gi... - gi|76609634|ref|XP_590969.2| PREDICTED: similar to Homeobox D4 [Bos taurus], gi|155371905|ref|NP_001...
148.0 [0..1] [218..3]
gi|116294310 - gi|116294310|gb|AAP79287.2| hox 7 [Saccoglossus kowalevskii]
146.0 [0..1] [220..1]
HXD4_PANPA - Homeobox protein Hox-D4 OS=Pan paniscus GN=HOXD4 PE=3 SV=1
HXD4_PANTR - Homeobox protein Hox-D4 OS=Pan troglodytes GN=HOXD4 PE=3 SV=1
146.0 [0..1] [218..3]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYVANSFY KQSPNIPAYN MQTCGNYGSA SEVQASRYCY GGLDLSITFP PPAPSNSLHG  60
   61 VDMAANPRAH PDRPACSAAA APGHALGRDE AAPLNPGMYS QKAARPALEE RAKSSGEIKE 120
  121 EQAQTGQPAG LSQPPAPPQI YPWMTKLHMS HETD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-222]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKRSRTSYTR YQTLELEKEF HFNRYLTRRR RIEIANNLCL NERQIKIWFQ NRRMKWKKDS  60
   61 KMKSKEAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.221849
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle