YRC Public Data Repository - Protein Structure Prediction

Protein:	NRL_MOUSE
Organism:	Mus musculus
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NRL_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|26336306 - gi\|26336306\|dbj\|BAC31838.1\| unnamed protein product [Mus musculus]	206.0	[0..1]	[237..1]
gi\|30584169, gi\|... - gi\|61370162\|gb\|AAX43447.1\| neural retina leucine zipper [synthetic construct], gi\|61370156\|gb\|AAX434...	204.0	[0..1]	[237..1]
gi\|114652258, gi... - gi\|114652262\|ref\|XP_001166039.1\| PREDICTED: neural retina leucine zipper isoform 2 [Pan troglodytes]... NRL - neural retina leucine zipper gi\|208966846, gi... - gi\|61360347\|gb\|AAX41847.1\| neural retina leucine zipper [synthetic construct], gi\|61360341\|gb\|AAX418...	204.0	[0..1]	[237..1]
gi\|57090455 - gi\|57090455\|ref\|XP_547742.1\| PREDICTED: similar to Neural retina-specific leucine zipper protein (NR...	198.0	[0..1]	[237..1]
gi\|27700060, gi\|... - gi\|27700060\|ref\|XP_224189.1\| PREDICTED: similar to Neural retina-specific leucine zipper protein (NR...	197.0	[0..1]	[237..1]
gi\|109083087, gi... - gi\|109083089\|ref\|XP_001111646.1\| PREDICTED: neural retina leucine zipper isoform 3 [Macaca mulatta],...	195.0	[0..1]	[237..1]
gi\|76626842 - gi\|76626842\|ref\|XP_599808.2\| PREDICTED: similar to Neural retina-specific leucine zipper protein (NR...	190.0	[0..1]	[226..1]
MAFA_XENTR - Transcription factor MafA OS=Xenopus tropicalis GN=mafa PE=2 SV=1	161.0	[0..3]	[230..11]
MAFA_COTJA - Transcription factor MafA OS=Coturnix coturnix japonica GN=MAFA PE=1 SV=1	158.0	[0..3]	[226..11]
gi\|12381859, gi\|... - gi\|56790311\|ref\|NP_571920.1\| v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein ...	157.0	[0..3]	[233..11]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFPPSPLAM EYVNDFDLMK FEIKREPSEG RSGVPTASLG STPYSSVPPS PTFSEPGMVG  60
   61 GGEAPRPGLE ELYWLATLQQ QLGSDEVLGL SPDEAVELLQ NQGPVSMEGP LGYYSGSPGE 120
  121 TGAQHVQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.435	0.149	positive regulation of transcription from RNA polymerase II promoter	c.95.1	Thiolase-like
View	Download	0.273	0.057	positive regulation of transcription from RNA polymerase II promoter	a.91.1	Regulator of G-protein signalling, RGS
View	Download	0.226	0.030	positive regulation of transcription from RNA polymerase II promoter	a.36.1	Signal peptide-binding domain
View	Download	0.249	0.020	positive regulation of transcription from RNA polymerase II promoter	c.23.4	Succinyl-CoA synthetase domains
View	Download	0.354	N/A	N/A	c.95.1	Thiolase-like

Predicted Domain #2

Region A:
Residues: [128-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPERFSDAAL VSMSVRELNR QLRGCGRDEA LRLKQRRRTL KNRGYAQACR SKRLQQRRGL  60
   61 EAERARLAAQ LDALRAEVAR LARERDLYKA RCDRLTSGGP GSDDHTHLFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.154902
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits