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View Structure Prediction Details

Protein: KRT73
Organism: Homo sapiens
Length: 540 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRT73.

Description E-value Query
Range
Subject
Range
gi|109096837 - gi|109096837|ref|XP_001098388.1| PREDICTED: similar to keratin 6 irs3 [Macaca mulatta]
8.0E-89 [1..540] [1..540]
gi|114644558 - gi|114644558|ref|XP_001142875.1| PREDICTED: keratin 6 irs3 [Pan troglodytes]
5.0E-88 [1..540] [1..540]
gi|73996467 - gi|73996467|ref|XP_850012.1| PREDICTED: similar to keratin 6 irs3 [Canis familiaris]
2.0E-85 [1..540] [1..540]
K2C73_BOVIN - Keratin, type II cytoskeletal 73 OS=Bos taurus GN=KRT73 PE=2 SV=1
4.0E-80 [1..540] [1..540]
K2C73_RAT - Keratin, type II cytoskeletal 73 OS=Rattus norvegicus GN=Krt73 PE=1 SV=1
3.0E-79 [1..540] [1..539]
K2C73_MOUSE - Keratin, type II cytoskeletal 73 OS=Mus musculus GN=Krt73 PE=1 SV=1
6.0E-79 [1..540] [1..539]
KRT84 - keratin 84
5.0E-74 [1..534] [1..556]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRQFTYKSG AAAKGGFSGC SAVLSGGSSS SYRAGGKGLS GGFSSRSLYS LGGARSISFN  60
   61 VASGSGWAGG YGFGRGRASG FAGSMFGSVA LGSVCPSLCP PGGIHQVTIN KSLLAPLNVE 120
  121 LDPEIQKVRA QER

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [134-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQIKVLNNKF ASFIDKVRFL EQQNQVLETK WELLQQLDLN NCKNNLEPIL EGYISNLRKQ  60
   61 LETLSGDRVR LDSELRSVRE VVEDYKKRYE EEINKRTTAE NEFVVLKKDV DAAYTSKVEL 120
  121 QAKVDALDGE IKFFKCLYEG ETAQIQSHIS DTSIILSMDN NRNLDLDSII AEVRAQYEEI 180
  181 ARKSKAEAEA LYQTKFQELQ LAAGRHGDDL KHTKNEISEL TRLIQRLRSE IESVKKQCAN 240
  241 LETAIADAEQ RGDCALKDAR AKLDELEGAL QQAKEELARM LREYQELLSV KLSLDIEIAT 300
  301 YRKLLEGEEC RMSGEYTNSV SISVINSSMA GMAGTGAGFG FSNAGTYGYW PSSVSGGYSM 360
  361 LPGGCVTGSG NCSPRGEART RLGSASEFRD SQGKTLALSS PTKKTMR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle