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View Structure Prediction Details

Protein: gi|85567007, gi|...
Organism: Homo sapiens
Length: 1064 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|85567007, gi|....

Description E-value Query
Range
Subject
Range
PUM2 - pumilio homolog 2 (Drosophila)
871.0 [0..1] [1064..1]
gi|109102137, gi... - gi|109102137|ref|XP_001095963.1| PREDICTED: similar to pumilio homolog 2 isoform 4 [Macaca mulatta],...
870.0 [0..1] [1064..1]
gi|114576341, gi... - gi|114576341|ref|XP_001140758.1| PREDICTED: pumilio homolog 2 isoform 11 [Pan troglodytes], gi|11457...
869.0 [0..1] [1064..1]
gi|73979795 - gi|73979795|ref|XP_849088.1| PREDICTED: similar to pumilio homolog 2 isoform 1 [Canis familiaris]
860.0 [0..1] [1064..1]
gi|74200874, gi|... - gi|74200874|dbj|BAE24797.1| unnamed protein product [Mus musculus], gi|237649085|ref|NP_001153693.1|...
845.0 [0..1] [1064..1]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW GASHHSMSQP  60
   61 IMVQRRSGQG FHGNSEVNAI LSPRSESGGL GVSMVEYVLS SSPADKLDSR FRKGNFGTRD 120
  121 AETDGPEKGD QKGKASPFEE DQNRDLKQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [149-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDDDDSKING RGLPNGMDAD CKDFNRTPGS RQASPTEVVE RLGPNTNPSE GLGPLPNPTA  60
   61 NKPLVEEFSN PETQNLDAME QVGLESLQFD YPGNQVPMDS SGATVGLFDY NSQQQLFQRT 120
  121 NALTVQQLTA AQQQQYALAA AQQPHIAGVF SAGLAPAAFV PNPYIISAAP PGTDPYTAAG 180
  181 LAAAATLAGP AVVPPQYYGV PWG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [352-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYPANLFQQQ AAAAANNTAS QQAASQAQPG QQQVLRAGAG QRPLTPNQGQ QGQQAESLAA  60
   61 AAAANPTLAF GQGLATGMPG YQVLAPTAYY DQTGALVVGP GARTGLGAPV RLMAPTPVLI 120
  121 SSAAAQAAAA AAAGGTASSL TGSTNGLFRP IGTQPPQQQQ QQPSTNLQSN SFYGSSSLTN 180
  181 SSQSSSLFSH GPGQPGSTSL GFGSGNSLGA AIGSALSGFG SSVGSSASSS A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [583-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRRESLSTSS DLYKRSSSSL APIGQPFYNS LGFSSSPSPI GMPLPSQTPG HSLTPPPSLS  60
   61 SHGSSSSLHL GGLTNGSGRY ISAAPGAEAK YRSASSTSSL FSSSSQLFPP SRLRYNRSDI 120
  121 MPSGRSRLLE DFRNNRFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [721-1064]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLQLRDLIGH IVEFSQDQHG SRFIQQKLER ATPAERQMVF NEILQAAYQL MTDVFGNYVI  60
   61 QKFFEFGSLD QKLALATRIR GHVLPLALQM YGCRVIQKAL ESISSDQQSE MVKELDGHVL 120
  121 KCVKDQNGNH VVQKCIECVQ PQSLQFIIDA FKGQVFVLST HPYGCRVIQR ILEHCTAEQT 180
  181 LPILEELHQH TEQLVQDQYG NYVIQHVLEH GRPEDKSKIV SEIRGKVLAL SQHKFASNVV 240
  241 EKCVTHASRA ERALLIDEVC CQNDGPHSAL YTMMKDQYAN YVVQKMIDMA EPAQRKIIMH 300
  301 KIRPHITTLR KYTYGKHILA KLEKYYLKNS PDLGPIGGPP NGML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 155.0
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle