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View Structure Prediction Details

Protein: HDAC7A
Organism: Homo sapiens
Length: 952 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDAC7A.

Description E-value Query
Range
Subject
Range
gi|224487805 - gi|224487805|dbj|BAH24137.1| histone deacetylase 7 [synthetic construct]
gi|194387788, gi... - gi|33415445|gb|AAQ18232.1| histone deacetylase [Homo sapiens], gi|194387788|dbj|BAG61307.1| unnamed ...
0.0 [1..952] [40..991]
gi|26331526 - gi|26331526|dbj|BAC29493.1| unnamed protein product [Mus musculus]
0.0 [1..952] [1..946]
gi|73996686 - gi|73996686|ref|XP_543715.2| PREDICTED: similar to histone deacetylase 7A isoform a isoform 1 [Canis...
0.0 [1..952] [1..962]
gi|114645025 - gi|114645025|ref|XP_522368.2| PREDICTED: similar to histone deacetylase [Pan troglodytes]
0.0 [1..952] [239..1190]
gi|109482809, gi... - gi|62653005|ref|XP_345869.2| PREDICTED: similar to Histone deacetylase 7a (HD7a) [Rattus norvegicus]...
0.0 [1..952] [1..953]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLRVGQRPP VEPPPEPTLL ALQRPQRLHH HLFLAGLQQQ RSVEPMRLSM DTPMPELQVG  60
   61 PQEQELRQLL HKDKSKRSAV ASSVVKQKLA EVILKKQQAA LERTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [106-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPNSPGIPYR TLEPLETEGA TRSMLSSFLP PVPSLPSDPP EHFPLRKTVS EPNLKLRYKP  60
   61 KKSLERRKNP LLRKESAPPS LRRRPAETLG DSSPSSSSTP ASGCSSPNDS EHGPNPILGS 120
  121 EALLGQRLRL QETSVAPFAL PTVSLLPAIT LGLPAPARAD SDRRTHPTLG PRGPILGSPH 180
  181 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [287-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLFLPHGLEP EAGGTLPSRL QPILLLDPSG SHAPLLTVPG LGPLPFHFAQ SLMTTERLSG  60
   61 SGLHWPLSRT RSEPLPPSAT APPPPGPMQP RLEQLKTHVQ VIKRSAKPSE KPRLRQIPSA 120
  121 EDLETDGGGP GQVVDDGLEH RELGHGQPEA RGPA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [441-952]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLQQHPQVLL WEQQRLAGRL PRGSTGDTVL LPLAQGGHRP LSRAQSSPAA PASLSAPEPA  60
   61 SQARVLSSSE TPARTLPFTT GLIYDSVMLK HQCSCGDNSR HPEHAGRIQS IWSRLQERGL 120
  121 RSQCECLRGR KASLEELQSV HSERHVLLYG TNPLSRLKLD NGKLAGLLAQ RMFVMLPCGG 180
  181 VGVDTDTIWN ELHSSNAARW AAGSVTDLAF KVASRELKNG FAVVRPPGHH ADHSTAMGFC 240
  241 FFNSVAIACR QLQQQSKASK ILIVDWDVHH GNGTQQTFYQ DPSVLYISLH RHDDGNFFPG 300
  301 SGAVDEVGAG SGEGFNVNVA WAGGLDPPMG DPEYLAAFRI VVMPIAREFS PDLVLVSAGF 360
  361 DAAEGHPAPL GGYHVSAKCF GYMTQQLMNL AGGAVVLALE GGHDLTAICD ASEACVAALL 420
  421 GNRVDPLSEE GWKQKPNLNA IRSLEAVIRV HSKYWGCMQR LASCPDSWVP RVPGADKEEV 480
  481 EAVTALASLS VGILAEDRPS EQLVEEEEPM NL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.0
Match: 2nvrA
Description: No description for 2nvrA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle