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View Structure Prediction Details

Protein: OTUD5
Organism: Homo sapiens
Length: 571 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OTUD5.

Description E-value Query
Range
Subject
Range
gi|76659469 - gi|76659469|ref|XP_585195.2| PREDICTED: similar to OTU domain containing 5 isoform 2 [Bos taurus]
0.0 [49..571] [49..571]
gi|7673616 - gi|7673616|gb|AAF66952.1|AF229642_1 DXImx46e protein [Mus musculus]
0.0 [198..571] [7..375]
gi|6808165, gi|1... - gi|6808165|emb|CAB70778.1| hypothetical protein [Homo sapiens], pir||T46265 hypothetical protein DKF...
0.0 [140..571] [1..427]
gi|57111761 - gi|57111761|ref|XP_538031.1| PREDICTED: similar to CG6091-PA, isoform A isoform 1 [Canis familiaris]
0.0 [49..571] [49..566]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTILPKKKPP PPDADPANEP PPPGPMPPAP RRGGGVGVGG GGTGVGGGDR DRDSGVVGAR  60
   61 PRASPPPQGP LPGPPGALHR WALAVPPGAV AGPRPQQASP PPCGGPGGPG GGPGDALGAA 120
  121 AAGVGAAGVV VGVGGAVGVG GCCSGPGHSK RRRQAPGVGA VGGGSPEREE VGAGYNSEDE 180
  181 YEAAAARIEA MDPATVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [198-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQEHWFEKAL RDKKGFIIKQ MKEDGACLFR AVADQVYGDQ DMHEVVRKHC MDYLMKNADY  60
   61 FSNYVTEDFT TYINRKRKNN CHGNHIEMQA MAEMYNRPVE VYQYSTGTSA VEPINTFHGI 120
  121 HQNEDEPIRV SYHRNIHYNS VVNPNKATIG VGLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.529663942126259 bayes_pls_golite062009
hydrolase activity 0.16837900182603 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [352-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSFKPGFAE QSLMKNAIKT SEESWIEQQM LEDKKRATDW EATNEAIEEQ VARESYLQWL  60
   61 RDQEKQARQV RGPSQPRKAS ATCSSATAAA SSGLEEWTSR SPRQRSSASS PEHPELHAEL 120
  121 G

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 1q1qA
Description: Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [473-571]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPPSPGTVL ALAKPPSPCA PGTSSQFSAG ADRATSPLVS LYPALECRAL IQQMSPSAFG  60
   61 LNDWDDDEIL ASVLAVSQQE YLDSMKKNKV HRDPPPDKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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