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View Structure Prediction Details

Protein: NPM1
Organism: Homo sapiens
Length: 294 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPM1.

Description E-value Query
Range
Subject
Range
gi|197101984 - gi|197101984|ref|NP_001125077.1| nucleophosmin (nucleolar phosphoprotein B23, numatrin) [Pongo abeli...
gi|55726890 - gi|55726890|emb|CAH90204.1| hypothetical protein [Pongo abelii]
0.0 [1..294] [1..295]
gi|30584325, gi|... - gi|60653673|gb|AAX29530.1| nucleophosmin [synthetic construct], gi|30584325|gb|AAP36411.1| Homo sapi...
0.0 [1..294] [1..294]
gi|16876992 - gi|16876992|gb|AAH16768.1| Nucleophosmin (nucleolar phosphoprotein B23, numatrin) [Homo sapiens]
0.0 [1..294] [1..294]
gi|94386888, gi|... - gi|94386888|ref|XP_979585.1| PREDICTED: similar to Nucleophosmin (NPM) (Nucleolar phosphoprotein B23...
0.0 [1..294] [1..284]
gi|109079755 - gi|109079755|ref|XP_001095288.1| PREDICTED: similar to nucleophosmin 1 isoform 2 [Macaca mulatta]
0.0 [1..294] [130..394]
NPM_RAT - Nucleophosmin OS=Rattus norvegicus GN=Npm1 PE=1 SV=1
0.0 [1..294] [1..292]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV  60
   61 EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE 120
  121 ED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.39794
Match: 2p1bA
Description: No description for 2p1bA was found.

Predicted Domain #2
Region A:
Residues: [123-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AESEDEEEED VKLLSISGKR SAPGGGSKVP QKKVKLAADE DDDDDDEEDD DEDDDDDDFD  60
   61 DEEAEEKAPV KKSIRDTPAK NAQKSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [209-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNGKDSKPSS TPRSKGQESF KKQEKTPKTP KGPSSVEDIK AKMQASIEKG GSLPKVEAKF  60
   61 INYVKNCFRM TDQEAIQDLW QWRKSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.587 0.567 protein heterodimerization activity a.118.1 ARM repeat
View Download 0.493 0.119 cell aging a.29.2 Bromodomain
View Download 0.430 0.024 centrosome cycle a.118.8 TPR-like
View Download 0.426 0.002 centrosome cycle a.118.11 Cytochrome c oxidase subunit E
View Download 0.378 N/A N/A a.29.2 Bromodomain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle