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View Structure Prediction Details

Protein: gi|14595019, gi|...
Organism: Homo sapiens
Length: 523 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14595019, gi|....

Description E-value Query
Range
Subject
Range
KRT73 - keratin 73
2.0E-76 [1..523] [1..540]
gi|109096837 - gi|109096837|ref|XP_001098388.1| PREDICTED: similar to keratin 6 irs3 [Macaca mulatta]
3.0E-76 [1..523] [1..540]
gi|114644558 - gi|114644558|ref|XP_001142875.1| PREDICTED: keratin 6 irs3 [Pan troglodytes]
1.0E-75 [1..523] [1..540]
gi|57106717 - gi|57106717|ref|XP_543652.1| PREDICTED: similar to Keratin, type II cuticular Hb4 (Hair keratin, typ...
4.0E-75 [1..458] [1..478]
gi|190692003, gi... - gi|254071365|gb|ACT64442.1| keratin 71 protein [synthetic construct], gi|190692003|gb|ACE87776.1| ke...
gi|55727226 - gi|55727226|emb|CAH90369.1| hypothetical protein [Pongo abelii]
KRT71 - keratin 71
K2C71_PONAB - Keratin, type II cytoskeletal 71 OS=Pongo abelii GN=KRT71 PE=2 SV=1
2.0E-73 [1..523] [1..523]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRQFTCKSG AAAKGGFSGC SAVLSGGSSS SFRAGSKGLS GGFGSRSLYS LGGVRSLNVA  60
   61 SGSGKSGGYG FGRGRASGFA GSMFGSVALG PVCPTVC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGGIHQVTV NESLLAPLNV ELDPEIQKVR AQEREQIKAL NNKFASFIDK VRFLEQQNQV  60
   61 LETKWELLQQ LDLNNCKNNL EPILEGYISN LRKQLETLSG DRVRLDSELR NVRDVVEDYK 120
  121 KRYEEEINKR TAAENEFVLL KKDVDAAYAN KVELQAKVES MDQEIKFFRC LFEAEITQIQ 180
  181 SHISDMSVIL SMDNNRNLDL DSIIDEVRTQ YEEIALKSKA EAEALYQTKF QELQLAAGRH 240
  241 GDDLKNTKNE ISELTRLIQR IRSEIENVKK QASNLETAIA DAEQRGDNAL KDARAKLDEL 300
  301 EGALHQAKEE LARMLREYQE LMSLKLALDM EIATYRKLLE SEECRMSGEF PSPVSISIIS 360
  361 STSGGSVYGF RPSMVSGGYV ANSSNCISGV CSVRGGEGRS RGSANDYKDT LGKGSSLSAP 420
  421 SKKTSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle