YRC Public Data Repository - Protein Structure Prediction

Protein:	TWSG1
Organism:	Homo sapiens
Length:	223 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TWSG1.

Description	E-value	Query Range	Subject Range
gi\|109121565 - gi\|109121565\|ref\|XP_001099214.1\| PREDICTED: similar to twisted gastrulation [Macaca mulatta] gi\|90079225 - gi\|90079225\|dbj\|BAE89292.1\| unnamed protein product [Macaca fascicularis] gi\|114672282 - gi\|114672282\|ref\|XP_001138675.1\| PREDICTED: twisted gastrulation [Pan troglodytes]	2.0E-96	[1..223]	[1..223]
gi\|22761772 - gi\|22761772\|dbj\|BAC11693.1\| unnamed protein product [Homo sapiens]	5.0E-96	[1..223]	[1..223]
TWSG1_PONAB - Twisted gastrulation protein homolog 1 OS=Pongo abelii GN=TWSG1 PE=2 SV=1 TWSG1_PONPY - Twisted gastrulation protein homolog 1 precursor - Pongo pygmaeus (Orangutan)	1.0E-95	[1..223]	[1..223]
gi\|73962202 - gi\|73962202\|ref\|XP_547668.2\| PREDICTED: similar to twisted gastrulation [Canis familiaris]	5.0E-94	[1..223]	[1..223]
gi\|115497310, gi... - gi\|76651994\|ref\|XP_617448.2\| PREDICTED: similar to twisted gastrulation [Bos taurus], gi\|115497310\|r...	6.0E-93	[1..223]	[1..223]
gi\|149037370, gi... - gi\|34877944\|ref\|XP_343638.1\| PREDICTED: similar to twisted gastrulation homolog 1 [Rattus norvegicus...	2.0E-91	[1..223]	[1..222]
TWSG1_MOUSE - Twisted gastrulation protein homolog 1 OS=Mus musculus GN=Twsg1 PE=1 SV=1	1.0E-90	[1..223]	[1..222]

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Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLHYVAVLT LAILMFLTWL PESLSCNKAL CASDVSKCLI QELCQCRPGE GNCSCCKECM  60
   61 LCLGALWDEC CDCVGMCNPR NYS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [84-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTPPTSKSTV EELHEPIPSL FRALTEGDTQ LNWNIVSFPV AEELSHHENL VSFLETVNQP  60
   61 HHQNVSVPSN NVHAPYSSDK EHMCTVVYFD DCMSIHQCKI SCESMGASKY RWFHNACCEC 120
  121 IGPECIDYGS KTVKCMNCMF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	104.200659
Match:	PF04668.3
Description:	No description for PF04668.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits