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View Structure Prediction Details

Protein: UGT1A1
Organism: Homo sapiens
Length: 533 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UGT1A1.

Description E-value Query
Range
Subject
Range
gi|7447698 - gi|7447698|pir||JC5656 UDP glucuronosyltransferase (EC 2.4.1.-) 1A10 precursor - human
0.0 [1..533] [1..530]
UD11_MOUSE - UDP-glucuronosyltransferase 1-1 OS=Mus musculus GN=Ugt1a1 PE=1 SV=2
0.0 [18..533] [20..535]
gi|149037676, gi... - gi|89276785|ref|NP_787040.2| UDP glycosyltransferase 1 family, polypeptide A8 [Rattus norvegicus], g...
0.0 [1..533] [1..530]
gi|114584009 - gi|114584009|ref|XP_001151230.1| PREDICTED: UDP glycosyltransferase 1 family, polypeptide A1 isoform...
0.0 [1..533] [1..533]

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Predicted Domain #1
Region A:
Residues: [1-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVESQGGRP LVLGLLLCVL GPVVSHAGKI LLIPVDGSHW LSMLGAIQQL QQRGHEIVVL  60
   61 APDASLYIRD GAFYTLKTYP VPFQREDVKE SFVSLGHNVF ENDSFLQRVI KTYKKIKKDS 120
  121 AMLLSGCSHL LHNKELMASL AESSFDVMLT DPFLPCSPIV AQYLSLPTVF FLHALPCSLE 180
  181 FEATQCPNPF SYVPRPLSSH SDHMTFLQRV KNMLIAFSQN FLCDVVYSPY ATLASEFLQR 240
  241 EVTVQDLLSS ASVWLFRSDF VKDYPRPIMP NMVFVGGINC LH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.61
Match: 2iyaA
Description: No description for 2iyaA was found.

Predicted Domain #2
Region A:
Residues: [283-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNPLSQEFEA YINASGEHGI VVFSLGSMVS EIPEKKAMAI ADALGKIPQT VLWRYTGTRP  60
   61 SNLANNTILV KWLPQNDLLG HPMTRAFITH AGSHGVYESI CNGVPMVMMP LFGDQMDNAK 120
  121 RMETKGAGVT LNVLEMTSED LENALKAVIN DKSYKENIMR LSSLHKDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.09691
Match: 2o6lA
Description: No description for 2o6lA was found.

Predicted Domain #3
Region A:
Residues: [451-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVEPLDLAVF WVEFVMRHKG APHLRPAAHD LTWYQYHSLD VIGFLLAVVL TVAFITFKCC  60
   61 AYGYRKCLGK KGRVKKAHKS KTH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle