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View Structure Prediction Details

Protein: DPP3
Organism: Homo sapiens
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPP3.

Description E-value Query
Range
Subject
Range
gi|57997190 - gi|57997190|emb|CAI46122.1| hypothetical protein [Homo sapiens]
0.0 [1..737] [1..737]
gi|55727688 - gi|55727688|emb|CAH90596.1| hypothetical protein [Pongo abelii]
gi|197098226 - gi|197098226|ref|NP_001125322.1| dipeptidyl-peptidase 3 [Pongo abelii]
0.0 [1..737] [1..737]
DPP3_RAT - Dipeptidyl peptidase 3 OS=Rattus norvegicus GN=Dpp3 PE=1 SV=2
0.0 [1..737] [1..738]
gi|45219731 - gi|45219731|gb|AAH66817.1| Dipeptidylpeptidase 3 [Mus musculus]
0.0 [1..737] [1..738]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTQYILPN DIGVSSLDCR EAFRLLSPTE RLYAYHLSRA AWYGGLAVLL QTSPEAPYIY  60
   61 ALLSRLFRAQ DPDQLRQHAL AEGLTEEEYQ AFLVYAAGVY SNMGNYKSFG DTKFVPNLPK 120
  121 EKLERVILGS EAAQQHPEEV RGLWQTCGEL MFSLEPRLRH LGLGKEGITT YF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [173-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGNCTMEDAK LAQDFLDSQN LSAYNTRLFK EVDGEGKPYY EVRLASVLGS EPSLDSEVTS  60
   61 KLKSYEFRGS PFQVTRGDYA PILQKVVEQL EKAKAYAANS HQGQMLAQYI ESFTQGSIEA 120
  121 HKRGSRFWIQ DKGPIVESYI GFIESYRDPF GS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [325-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGEFEGFVAV VNKAMSAKFE RLVASAEQLL KELPWPPTFE KDKFLTPDFT SLDVLTFAGS  60
   61 GIPAGINIPN YDDLRQTEGF KNVSLGNVLA VAYATQR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [422-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKLTFLEEDD KDLYILWKGP SFDVQVGLHE LLGHGSGKLF VQDEKGAFNF DQETVINPET  60
   61 GEQIQSWYRS GETWDSKFST IASSYEECRA ESVGLYLCLH PQVLEIFGFE GAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.405 0.902 aminopeptidase activity a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #5
Region A:
Residues: [535-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEDVIYVNWL NMVRAGLLAL EFYTPEAFNW RQAHMQARFV ILRVLLEAGE GLVTITPTTG  60
   61 SDGRPDARVR LDRSKIRSVG KPALERFLRR LQVLKSTGDV AGGRALYEGY ATVTDAPPEC 120
  121 FLTLRDTVLL RKESRKLIVQ PNTRLEGSDV QLLEYEASAA GLIRSFSERF PEDGPELEEI 180
  181 LTQLATADAR FWKGPSEAPS GQA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle