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View Structure Prediction Details

Protein: EXOC4
Organism: Homo sapiens
Length: 974 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXOC4.

Description E-value Query
Range
Subject
Range
gi|45595700 - gi|45595700|gb|AAH67263.1| Exocyst complex component 4 [Homo sapiens]
0.0 [1..974] [1..974]
gi|114616017 - gi|114616017|ref|XP_001139207.1| PREDICTED: hypothetical protein isoform 12 [Pan troglodytes]
0.0 [1..974] [1..974]
EXOC4_MOUSE - Exocyst complex component 4 OS=Mus musculus GN=Exoc4 PE=1 SV=2
0.0 [1..974] [1..975]
gi|197097498 - gi|197097498|ref|NP_001125023.1| exocyst complex component 4 [Pongo abelii]
gi|55726728 - gi|55726728|emb|CAH90126.1| hypothetical protein [Pongo abelii]
0.0 [1..974] [1..974]
gi|73975675 - gi|73975675|ref|XP_539369.2| PREDICTED: similar to Exocyst complex component Sec8 [Canis familiaris]
0.0 [1..974] [1..975]
EXOC4_RAT - Exocyst complex component 4 OS=Rattus norvegicus GN=Exoc4 PE=1 SV=1
0.0 [1..974] [1..975]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA YEKCDRDLDE  60
   61 LIVQHYTELT TAIRTYQSIT ERITNSRNKI KQVKEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [97-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLSCKMLLHC KRDELRKLWI EGIEHKHVLN LLDEIENIKQ VPQKLEQCMA SKHYLSATDM  60
   61 LVSAVESLEG PLLQVEGLSD LRLELHSKKM NLHLVLIDEL HRHLYIKSTS RVVQRNKEKG 120
  121 KISSLVKDAS VPLIDVTNLP TPRKFLDTSH YSTAGSSSVR EINLQDIKED LELDPEENST 180
  181 LFMGILIKGL AKLKKIPETV KAIIERLEQE LKQIVKRSTT QVADSGYQRG ENVTVENQPR 240
  241 LLLELLELLF DKFNAVAAAH SVVLGYLQDT VVTPLTQQED IKLYDMADVW VKIQDVLQML 300
  301 LTEYLDMKNT RTASEPSAQL SYASTGREFA AFFAKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.154902
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [433-662]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPQRPKNSLF KFESSSHAIS MSAYLREQRR ELYSRSGELQ GGPDDNLIEG GGTKFVCKPG  60
   61 ARNITVIFHP LLRFIQEIEH ALGLGPAKQC PLREFLTVYI KNIFLNQVLA EINKEIEGVT 120
  121 KTSDPLKILA NADTMKVLGV QRPLLQSTII VEKTVQDLLN LMHDLSAYSD QFLNMVCVKL 180
  181 QEYKDTCTAA YRGIVQSEEK LVISASWAKD DDISRLLKSL PNWMNMAQPK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [663-731]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLRPKREEEE DFIRAAFGKE SEVLIGNLGD KLIPPQDILR DVSDLKALAN MHESLEWLAS  60
   61 RTKSAFSNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [732-974]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSQMLSPAQ DSHTNTDLPP VSEQIMQTLS ELAKSFQDMA DRCLLVLHLE VRVHCFHYLI  60
   61 PLAKEGNYAI VANVESMDYD PLVVKLNKDI SAIEEAMSAS LQQHKFQYIF EGLGHLISCI 120
  121 LINGAQYFRR ISESGIKKMC RNIFVLQQNL TNITMSREAD LDFARQYYEM LYNTADELLN 180
  181 LVVDQGVKYT ELEYIHALTL LHRSQTGVGE LTTQNTRLQR LKEIICEQAA IKQATKDKKI 240
  241 TTV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle