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View Structure Prediction Details

Protein: COPB2
Organism: Homo sapiens
Length: 906 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COPB2.

Description E-value Query
Range
Subject
Range
gi|73990636 - gi|73990636|ref|XP_534283.2| PREDICTED: similar to coatomer protein complex, subunit beta 2 (beta pr...
0.0 [1..906] [1..906]
gi|55732092 - gi|55732092|emb|CAH92752.1| hypothetical protein [Pongo abelii]
COPB2_PONAB - Coatomer subunit beta' OS=Pongo abelii GN=COPB2 PE=2 SV=1
0.0 [1..906] [1..906]
COPB2_BOVIN - Coatomer subunit beta' - Bos taurus (Bovine)
0.0 [1..906] [1..906]
COPB2_MACFA - Coatomer subunit beta' OS=Macaca fascicularis GN=COPB2 PE=2 SV=1
0.0 [1..906] [1..906]
gi|114589653 - gi|114589653|ref|XP_516784.2| PREDICTED: coatomer protein complex, subunit beta 2 (beta prime) [Pan ...
0.0 [2..906] [130..1034]
COPB2_MOUSE - Coatomer subunit beta' OS=Mus musculus GN=Copb2 PE=1 SV=2
0.0 [1..906] [1..905]
gi|56789724 - gi|56789724|gb|AAH88397.1| Coatomer protein complex, subunit beta 2 (beta prime) [Rattus norvegicus]
0.0 [1..906] [1..905]
gi|27697187, gi|... - gi|27697187|gb|AAH41755.1| Wu:fc55e05-prov protein [Xenopus laevis], gi|148223685|ref|NP_001080221.1...
0.0 [1..905] [1..915]
gi|73853866, gi|... - gi|73853866|ref|NP_001027518.1| hypothetical protein LOC613110 [Xenopus (Silurana) tropicalis], gi|6...
0.0 [1..906] [1..920]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV  60
   61 RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120
  121 MLIKLWDWDK KWSCSQVFEG HTHYVMQIVI NPKDNNQFAS ASLDRTIKVW QLGSSSPNFT 180
  181 LEGHEKGVNC IDYYSGGDKP YLISGADDRL VKIWDYQNKT CVQTLEGHAQ NVSCASFHPE 240
  241 LPIIITGSED GTVRIWHSST YRLESTLNYG MERVWCVASL RGSNNVALGY DEGSIIVKLG 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.045757
Match: 2gnqA
Description: No description for 2gnqA was found.

Predicted Domain #2
Region A:
Residues: [301-681]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REEPAMSMDA NGKIIWAKHS EVQQANLKAM GDAEIKDGER LPLAVKDMGS CEIYPQTIQH  60
   61 NPNGRFVVVC GDGEYIIYTA MALRNKSFGS AQEFAWAHDS SEYAIRESNS IVKIFKNFKE 120
  121 KKSFKPDFGA ESIYGGFLLG VRSVNGLAFY DWDNTELIRR IEIQPKHIFW SDSGELVCIA 180
  181 TEESFFILKY LSEKVLAAQE THEGVTEDGI EDAFEVLGEI QEIVKTGLWV GDCFIYTSSV 240
  241 NRLNYYVGGE IVTIAHLDRT MYLLGYIPKD NRLYLGDKEL NIISYSLLVS VLEYQTAVMR 300
  301 RDFSMADKVL PTIPKEQRTR VAHFLEKQGF KQQALTVSTD PEHRFELALQ LGELKIAYQL 360
  361 AVEAESEQKW KQLAELAISK C

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.09
Match: 1nexB
Description: Cdc4 F-box and linker domains; Cdc4 propeller domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [682-827]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFGLAQECLH HAQDYGGLLL LATASGNANM VNKLAEGAER DGKNNVAFMS YFLQGKVDAC  60
   61 LELLIRTGRL PEAAFLARTY LPSQVSRVVK LWRENLSKVN QKAAESLADP TEYENLFPGL 120
  121 KEAFVVEEWV KETHADLWPA KQYPLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 2fo7A
Description: Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [828-906]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPNEERNVME EGKDFQPSRS TAQQELDGKP ASPTPVIVAS HTANKEEKSL LELEVDLDNL  60
   61 ELEDIDTTDI NLDEDILDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle