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View Structure Prediction Details

Protein: ELAVL1
Organism: Homo sapiens
Length: 326 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ELAVL1.

Description E-value Query
Range		 Subject
Range
gi|5738249, gi|4... - gi|5738249|gb|AAD50313.1|AF176673_1 RNA-binding protein HuA [Gallus gallus], gi|45382283|ref|NP_9901...
 2.0E-53 [1..326] [1..326]
gi|73587279, gi|... - gi|73587279|gb|AAI02496.1| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R...
 2.0E-53 [1..326] [1..326]
ELAV1_MOUSE - ELAV-like protein 1 OS=Mus musculus GN=Elavl1 PE=1 SV=2
gi|83308037 - gi|83308037|emb|CAI77902.1| HuR RNA binding protein [Spalax judaei]
ELAV1_RAT - ELAV-like protein 1 OS=Rattus norvegicus GN=Elavl1 PE=1 SV=1
 2.0E-53 [1..326] [1..326]
gi|73986922 - gi|73986922|ref|XP_854218.1| PREDICTED: similar to ELAV-like protein 1 (Hu-antigen R) (HuR) isoform ...
 3.0E-53 [1..326] [1..326]
gi|608537, gi|21... - gi|608537|gb|AAA96942.1| ribonucleoprotein, pir||I51675 ribonucleoprotein - African clawed frog
 3.0E-53 [1..326] [1..326]
gi|67968717 - gi|67968717|dbj|BAE00717.1| unnamed protein product [Macaca fascicularis]
 4.0E-53 [1..326] [1..326]
gi|109496377, gi... - gi|109496377|ref|XP_001065476.1| PREDICTED: similar to ELAV (embryonic lethal, abnormal vision, Dros...
 4.0E-53 [1..326] [156..482]
gi|1022961 - gi|1022961|gb|AAB41913.1| HuR RNA binding protein
 5.0E-53 [1..326] [1..326]

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Predicted Domain #1
Region A:
Residues: [1-141] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNGYEDHMA EDCRGDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS  60
   61 LGYGFVNYVT AKDAERAINT LNGLRLQSKT IKVSYARPSS EVIKDANLYI SGLPRTMTQK 120
  121 DVEDMFSRFG RIINSRVLVD Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 1fnxH
Description: Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [142-231] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTGLSRGVAF IRFDKRSEAE EAITSFNGHK PPGSSEPITV KFAANPNQNK NVALLSQLYH  60
   61 SPARRFGGPV HHQAQRFRFS PMGVDHMSGL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.33
Match: 2fy1A
Description: No description for 2fy1A was found.

Predicted Domain #3
Region A:
Residues: [232-326] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGVNVPGNAS SGWCIFIYNL GQDADEGILW QMFGPFGAVT NVKVIRDFNT NKCKGFGFVT  60
   61 MTNYEEAAMA IASLNGYRLG DKILQVSFKT NKSHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 1d8zA
Description: Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation repressor activity, nucleic acid binding 0.461000905454505 bayes_pls_golite062009
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