YRC Public Data Repository - Protein Structure Prediction

Protein:	PAF1
Organism:	Homo sapiens
Length:	531 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PAF1.

Description	E-value	Query Range	Subject Range
gi\|21758435 - gi\|21758435\|dbj\|BAC05305.1\| unnamed protein product [Homo sapiens]	390.0	[0..1]	[370..1]
tr\|M3WDU4\|M3WDU4... - PAF1 homolog, Paf1/RNA polymerase II complex component OS=Felis catus GN=PAF1 PE=4 SV=1 gi\|73947660 - gi\|73947660\|ref\|XP_533675.2\| PREDICTED: similar to Paf1, RNA polymerase II associated factor, homolo...	334.0	[0..1]	[455..1]
gi\|12857167 - gi\|12857167\|dbj\|BAB30913.1\| unnamed protein product [Mus musculus]	334.0	[0..1]	[377..1]
PAF1_PONAB - RNA polymerase II-associated factor 1 homolog OS=Pongo abelii GN=PAF1 PE=2 SV=1 gi\|55728701 - gi\|55728701\|emb\|CAH91090.1\| hypothetical protein [Pongo abelii]	334.0	[0..1]	[517..1]
PAF1_RAT - RNA polymerase II-associated factor 1 homolog OS=Rattus norvegicus GN=Paf1 PE=2 SV=1	331.0	[0..1]	[455..1]
PAF1_BOVIN - RNA polymerase II-associated factor 1 homolog OS=Bos taurus GN=PAF1 PE=2 SV=1	331.0	[0..1]	[455..1]

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Predicted Domain #1

Region A:
Residues: [1-81]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPTIQTQAQ REDGHRPNSH RTLPERSGVV CRVKYCNSLP DIPFDPKFIT YPFDQNRFVQ  60
   61 YKATSLEKQH KHDLLTEPDL G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [82-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTIDLINPDT YRIDPNVLLD PADEKLLEEE IQAPTSSKRS QQHAKVVPWM RKTEYISTEF  60
   61 NRYGISNEKP EVKIGVSVKQ QFTEEEIYKD RDSQITAIEK TFEDAQKSIS QHYSKPRVTP 120
  121 VEVMPVFPDF KMWINPCAQV IFDSDPAPKD TSGAAALEMM SQAMIRGMMD EEGNQFVAYF 180
  181 L

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [263-383]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVEETLKKRK RDQEEEMDYA PDDVYDYKIA REYNWNVKNK ASKGYEENYF FIFREGDGVY  60
   61 YNELETRVRL SKRRAKAGVQ SGTNALLVVK HRDMNEKELE AQEARKAQLE NHEPEEEEEE 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [384-531]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEEKEAGG SDEEQEKGSS SEKEGSEDEH SGSESEREEG DRDEASDKSG SGEDESSEDE  60
   61 ARAARDKEEI FGSDADSEDD ADSDDEDRGQ AQGGSDNDSD SGSNGGGQRS RSHSRSASPF 120
  121 PSGSEHSAQE DGSEAAASDS SEADSDSD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits