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View Structure Prediction Details

Protein: gi|35167, gi|339...
Organism: Homo sapiens
Length: 463 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|35167, gi|339....

Description E-value Query
Range
Subject
Range
gi|1289508, gi|1... - gi|1289508|gb|AAB51352.1| pit-1/GHF-1, gi|112421204|ref|NP_001036325.1| pituitary specific transcrip...
5.0E-41 [5..346] [1..305]
gi|38181828 - gi|38181828|gb|AAH61564.1| Pou1f1 protein [Rattus norvegicus]
3.0E-40 [4..346] [19..324]
gi|170650730, gi... - gi|488129|dbj|BAA02291.1| pituitary-specific POU-domain DNA binding factor [Homo sapiens], gi|170650...
3.0E-40 [5..346] [1..305]
gi|88174213 - gi|88174213|gb|ABD39233.1| pituitary transcription factor 1 beta variant [Ovis aries]
8.0E-40 [5..349] [1..308]
gi|73947454 - gi|73947454|ref|XP_866309.1| PREDICTED: similar to POU domain, class 2, transcription factor 2 isofo...
9.0E-40 [1..463] [1..463]
PO2F2_MOUSE - POU domain, class 2, transcription factor 2 OS=Mus musculus GN=Pou2f2 PE=2 SV=4
2.0E-39 [1..463] [1..463]
gi|414330 - gi|414330|gb|AAA41734.1| octamer-binding transcription factor [Rattus sp.]
4.0E-39 [1..463] [1..463]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS  60
   61 TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL 120
  121 QPPAQFLLPQ AQQSQPGL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.45
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [139-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTPNLFQLP QQTQGALLTS QPRAGLPTQP PKCLEPPSHP EEPSDLEELE QFARTFKQRR  60
   61 IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW LNDAETMSVD 120
  121 SSLPSPNQLS SPSLGFDGLP GRRRKKRTSI ETNVRFALEK SFLANQKPTS EEILLIAEQL 180
  181 HMEKEVIRVW FCNRRQKEKR INPCSAAPML PSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.221849
Match: 1cqtA
Description: Oct-1 POU Homeodomain; Oct-1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [352-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKPASYSPHM VTPQGGAGTL PLSQASSSLS TTVTTLSSAV GTLHPSRTAG GGGGGGGAAP  60
   61 PLNSIPSVTP PPPATTNSTN PSPQGSHSAI GLSGLNPSTG PGLWWNPAPY QP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle