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View Structure Prediction Details

Protein: KRT36
Organism: Homo sapiens
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRT36.

Description E-value Query
Range
Subject
Range
gi|109115395 - gi|109115395|ref|XP_001106116.1| PREDICTED: similar to type I hair keratin 6 isoform 2 [Macaca mulat...
3.0E-66 [1..467] [1..467]
gi|73996557 - gi|73996557|ref|XP_850166.1| PREDICTED: similar to keratin, hair, basic, 3 [Canis familiaris]
2.0E-65 [6..406] [112..515]
gi|109481333 - gi|109481333|ref|XP_001064779.1| PREDICTED: similar to keratin Kb40 [Rattus norvegicus]
7.0E-65 [1..407] [149..569]
gi|42760016 - gi|42760016|emb|CAF31524.1| type II hair keratin 4 [Homo sapiens]
7.0E-63 [3..406] [68..476]
gi|114667403 - gi|114667403|ref|XP_001168025.1| PREDICTED: keratin 36 isoform 3 [Pan troglodytes]
9.0E-63 [1..467] [1..467]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATQTCTPTF STGSIKGLCG TAGGISRVSS IRSVGSCRVP SLAGAAGYIS SARSGLSGLG  60
   61 SCLPGSYLSS ECHTSGFVGS G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GWFCEGSFNG SEKETMQFLN DRLANYLEKV RQLERENAEL ESRIQEWYEF QIPYICPDYQ  60
   61 SYFKTIEDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [151-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQKILLTKSE NARLVLQIDN AKLAADDFRT KYETELSLRQ LVEADINGLR RILDELTLCK  60
   61 ADLEAQVESL KEELMCLKKN HEEEVSVLRC QLGDRLNVEV DAAPPVDLNK ILEDMRCQYE 120
  121 ALVENNRRDV EAWFNTQTEE LNQQVVSSSE QLQCCQTEII ELRRTVNALE IELQAQHSMR 180
  181 NSLESTLAET EARYSSQLAQ MQCLISNVEA QLSEIRCDLE RQNQEYQVLL DVKARLEGEI 240
  241 ATYRHLLEGE DCKLPPQPCA TACKPVIRVP SVPPVPCVPS VPCTPAPQVG TQIRTITEEI 300
  301 RDGKVISSRE HVQSRPL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle