YRC Public Data Repository - Protein Structure Prediction

Protein:	SETD4
Organism:	Homo sapiens
Length:	440 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SETD4.

Description	E-value	Query Range	Subject Range
gi\|114684042 - gi\|114684042\|ref\|XP_001168912.1\| PREDICTED: hypothetical protein isoform 9 [Pan troglodytes]	0.0	[1..440]	[1..440]
gi\|109065368 - gi\|109065368\|ref\|XP_001085715.1\| PREDICTED: hypothetical protein LOC54093 isoform 4 [Macaca mulatta]	0.0	[1..440]	[1..440]
gi\|167773807 - gi\|167773807\|gb\|ABZ92338.1\| SET domain containing 4 [synthetic construct] gi\|55953061, gi\|... - gi\|55953061\|ref\|NP_001007259.1\| hypothetical protein LOC54093 isoform b [Homo sapiens], gi\|22328112\|...	0.0	[25..440]	[1..416]
gi\|80479475 - gi\|80479475\|gb\|AAI08868.1\| Unknown (protein for MGC:132347) [Xenopus laevis]	0.0	[1..438]	[1..441]
SETD4_MOUSE - SET domain-containing protein 4 OS=Mus musculus GN=Setd4 PE=2 SV=1	0.0	[24..440]	[23..439]
gi\|74001422 - gi\|74001422\|ref\|XP_544872.2\| PREDICTED: similar to Protein C21orf18 [Canis familiaris]	0.0	[18..439]	[54..475]
gi\|166091525, gi... - gi\|166091525\|ref\|NP_001107219.1\| SET domain containing 4 [Rattus norvegicus], gi\|165971256\|gb\|AAI586...	0.0	[25..440]	[23..439]

Back

Predicted Domain #1

Region A:
Residues: [1-440]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKGKGRTSR IRRRKLCGSS ESRGVNESHK SEFIELRKWL KARKFQDSNL APACFPGTGR  60
   61 GLMSQTSLQE GQMIISLPES CLLTTDTVIR SYLGAYITKW KPPPSPLLAL CTFLVSEKHA 120
  121 GHRSLWKPYL EILPKAYTCP VCLEPEVVNL LPKSLKAKAE EQRAHVQEFF ASSRDFFSSL 180
  181 QPLFAEAVDS IFSYSALLWA WCTVNTRAVY LRPRQRECLS AEPDTCALAP YLDLLNHSPH 240
  241 VQVKAAFNEE THSYEIRTTS RWRKHEEVFI CYGPHDNQRL FLEYGFVSVH NPHACVYVSR 300
  301 EILVKYLPST DKQMDKKISI LKDHGYIENL TFGWDGPSWR LLTALKLLCL EAEKFTCWKK 360
  361 VLLGEVISDT NEKTSLDIAQ KICYYFIEET NAVLQKVSHM KDEKEALINQ LTLVESLWTE 420
  421 ELKILRASAE TLHSLQTAFT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.221849
Match:	1mlvA
Description:	RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.0186534007183686	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: