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View Structure Prediction Details

Protein: KRT6A
Organism: Homo sapiens
Length: 564 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRT6A.

Description E-value Query
Range
Subject
Range
gi|109096771 - gi|109096771|ref|XP_001093676.1| PREDICTED: keratin, hair, basic, 4 [Macaca mulatta]
1.0E-77 [1..478] [1..478]
KRT84 - keratin 84
9.0E-76 [1..478] [1..478]
gi|114644580 - gi|114644580|ref|XP_522389.2| PREDICTED: keratin, hair, basic, 4 [Pan troglodytes]
2.0E-75 [1..478] [1..478]
gi|57106717 - gi|57106717|ref|XP_543652.1| PREDICTED: similar to Keratin, type II cuticular Hb4 (Hair keratin, typ...
5.0E-74 [1..478] [1..465]
gi|46485108, gi|... - gi|57012366|ref|NP_001008812.1| keratin 84 [Rattus norvegicus], gi|46485108|tpg|DAA02223.1| TPA_exp:...
8.0E-72 [1..478] [1..490]
KRT84_MOUSE, K2H... - Keratin, type II cuticular Hb4 OS=Mus musculus GN=Krt84 PE=2 SV=1, (Q99M73) Keratin, type II cuticul...
3.0E-69 [1..549] [1..557]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTSTTIRS HSSSRRGFSA NSARLPGVSR SGFSSVSVSR SRGSGGLGGA CGGAGFGSRS  60
   61 LYGLGGSKRI SIGGGSCAIS GGYGSRAGGS YGFGGAGSGF GFGGGAGIGF GLGGGAGLAG 120
  121 GFGGPGFPVC PPGGIQEVTV NQSLLTPLNL QIDPTIQRVR AEEREQI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [168-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTLNNKFASF IDKVRFLEQQ NKVLETKWTL LQEQGTKTVR QNLEPLFEQY INNLRRQLDS  60
   61 IVGERGRLDS ELRGMQDLVE DFKNKYEDEI NKRTAAENEF VTLKKDVDAA YMNKVELQAK 120
  121 ADTLTDEINF LRALYDAELS QMQTHISDTS VVLSMDNNRN LDLDSIIAEV KAQYEEIAQR 180
  181 SRAEAESWYQ TKYEELQVTA GRHGDDLRNT KQEIAEINRM IQRLRSEIDH VKKQCANLQA 240
  241 AIADAEQRGE MALKDAKNKL EGLEDALQKA KQDLARLLKE YQELMNVKLA LDVEIATYRK 300
  301 LLEGEECRLN GEGVGQVNIS VVQSTVSSGY GGASGVGSGL GLGGGSSYSY GSGLGVGGGF 360
  361 SSSSGRAIGG GLSSVGGGSS TIKYTTTSSS SRKSYKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle