YRC Public Data Repository - Protein Structure Prediction

Protein:	CLIP3
Organism:	Homo sapiens
Length:	547 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLIP3.

Description	E-value	Query Range	Subject Range
gi\|73948435 - gi\|73948435\|ref\|XP_541680.2\| PREDICTED: similar to CLIP-170-related protein [Canis familiaris]	3.0E-81	[1..547]	[325..871]
CLR59_PONPY, CLI... - (Q5R686) Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa p... CLIP3_PONAB - CAP-Gly domain-containing linker protein 3 OS=Pongo abelii GN=CLIP3 PE=2 SV=1	1.0E-80	[1..547]	[1..547]
gi\|109124432, gi... - gi\|109124434\|ref\|XP_001101586.1\| PREDICTED: similar to CLIP-170-related protein isoform 5 [Macaca mu...	2.0E-80	[1..547]	[1..547]
gi\|74751825, gi\|... - gi\|74751825\|sp\|Q96DZ5\|CLR59_HUMAN Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (...	5.0E-80	[1..547]	[1..547]
gi\|76641374 - gi\|76641374\|ref\|XP_601255.2\| PREDICTED: similar to CLIP-170-related protein isoform 1 [Bos taurus]	5.0E-79	[1..547]	[1..547]
gi\|157819339, gi... - gi\|157819339\|ref\|NP_001100971.1\| CAP-GLY domain containing linker protein 3 [Rattus norvegicus], gi\|... CLIP3_MOUSE - CAP-Gly domain-containing linker protein 3 OS=Mus musculus GN=Clip3 PE=1 SV=1	5.0E-79	[1..547]	[1..547]
gi\|108868779, gi... - gi\|157106769\|ref\|XP_001649474.1\| ankyrin 2,3/unc44 [Aedes aegypti], gi\|108868779\|gb\|EAT33004.1\| anky...	6.0E-70	[13..403]	[13..373]
CLIP3_XENLA - CAP-Gly domain-containing linker protein 3 OS=Xenopus laevis GN=clip3 PE=2 SV=1	1.0E-68	[17..547]	[7..534]
gi\|68380790 - gi\|68380790\|ref\|XP_690922.1\| PREDICTED: hypothetical protein XP_685830 [Danio rerio]	2.0E-67	[11..547]	[41..584]

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Predicted Domain #1

Region A:
Residues: [1-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKTDPAPMA PPPRGEEEEE EEEDEPVPEA PSPTQERRQK PVVHPSAPAP LPKDYAFTFF  60
   61 DPNDPACQEI LFDPQTTIPE LFAIVRQWVP QVQHKIDVIG NEILRRGCHV NDRDGLTDMT 120
  121 LLHYACKAGA HGVGDPAAAV RLSQQLLALG ADVTLRSRWT NMNALHYAAY FDVPDLVRVL 180
  181 LKGARPRVVN STCSDFNHGS ALHIAASSLC LGAAKCLLEH GANPALRNRK GQVPAEVVPD 240
  241 PMDMSLDKAE AALVAKELRT LLEEAVPLSC ALPKVTLPNY DNVPGNLMLS ALGLRLGDRV 300
  301 LLDGQKTGTL RFCGTTEFAS GQWVGVELDE PEGKNDGSVG GVRYFICPPK QGLFASVSKI 360
  361 SKAVDAPPSS VTSTPRTPRM DFSRVTGKGR REHKGKKKTP SSPSLGSLQQ RDGAKAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.522879
Match:	1n11A
Description:	Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [418-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGDQVLVAGQ KQGIVRFYGK TDFAPGYWYG IELDQPTGKH DGSVFGVRYF TCPPRHGVFA  60
   61 PASRIQRIGG STDSPGDSVG AKKVHQVTMT QPKRTFTTVR TPKDIASENS ISRLLFCCWF 120
  121 PWMLRAEMQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	1whhA
Description:	Solution structure of the 2nd CAP-Gly domain in mouse CLIP170-related 59kDa protein CLIPR-59
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits