YRC Public Data Repository - Protein Structure Prediction

Protein:	MUTED
Organism:	Homo sapiens
Length:	187 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUTED.

Description	E-value	Query Range	Subject Range
gi\|21619084 - gi\|21619084\|gb\|AAH32438.1\| MUTED protein [Homo sapiens]	5.0E-91	[2..187]	[2..187]
BL1S5_MOUSE - Biogenesis of lysosome-related organelles complex 1 subunit 5 OS=Mus musculus GN=Bloc1s5 PE=1 SV=1	2.0E-89	[1..187]	[1..185]
BL1S5_RAT - Biogenesis of lysosome-related organelles complex 1 subunit 5 OS=Rattus norvegicus GN=Bloc1s5 PE=1 S...	1.0E-87	[1..187]	[1..187]
gi\|76651399 - gi\|76651399\|ref\|XP_581818.2\| PREDICTED: similar to Muted protein homolog [Bos taurus]	2.0E-73	[1..187]	[30..219]
gi\|74004051 - gi\|74004051\|ref\|XP_851825.1\| PREDICTED: similar to Muted protein homolog [Canis familiaris]	1.0E-72	[36..187]	[107..258]
BL1S5_CHICK - Biogenesis of lysosome-related organelles complex 1 subunit 5 OS=Gallus gallus GN=BLOC1S5 PE=2 SV=1	2.0E-52	[19..187]	[28..196]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGGTETPV GCEAAPGGGS KKRDSLGTAG SAHLIIKDLG EIHSRLLDHR PVIQGETRYF  60
   61 VKEFEEKRGL REMRVLENLK NMIHETNEHT LPKCRDTMRD SLSQVLQRLQ AANDSVCRLQ 120
  121 QREQERKKIH SDHLVASEKQ HMLQWDNFMK EQPNKRAEVD EEHRKAMERL KEQYAEMEKD 180
  181 LAKFSTF

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.15
Match:	1ya9A
Description:	Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits