YRC Public Data Repository - Protein Structure Prediction

Protein:	NANP
Organism:	Homo sapiens
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NANP.

Description	E-value	Query Range	Subject Range
gi\|109093182 - gi\|109093182\|ref\|XP_001101196.1\| PREDICTED: similar to haloacid dehalogenase-like hydrolase domain c...	7.0E-46	[1..248]	[1..248]
NANP_MOUSE - N-acylneuraminate-9-phosphatase OS=Mus musculus GN=Nanp PE=1 SV=1	2.0E-44	[1..247]	[1..247]
NANP_RAT - N-acylneuraminate-9-phosphatase OS=Rattus norvegicus GN=Nanp PE=1 SV=1	3.0E-44	[1..247]	[1..247]
gi\|73989867 - gi\|73989867\|ref\|XP_850213.1\| PREDICTED: similar to haloacid dehalogenase-like hydrolase domain conta...	4.0E-44	[1..248]	[1..248]
gi\|157279173, gi... - gi\|76632080\|ref\|XP_594694.2\| PREDICTED: similar to N-acetylneuraminic acid phosphatase [Bos taurus],...	1.0E-42	[1..248]	[1..248]
gi\|88795676, gi\|... - gi\|88795676\|ref\|ZP_01111369.1\| phosphoglycolate phosphatase [Alteromonas macleodii 'Deep ecotype'], ...	1.0E-41	[1..236]	[1..223]
GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G... GPH_HAEIN - Phosphoglycolate phosphatase OS=Haemophilus influenzae GN=gph PE=3 SV=1	7.0E-41	[1..237]	[1..224]
gi\|229811380, gi... - gi\|229845694\|ref\|ZP_04465817.1\| phosphoglycolate phosphatase [Haemophilus influenzae 6P18H1], gi\|229... gi\|144985848, gi... - gi\|145633479\|ref\|ZP_01789208.1\| phosphoglycolate phosphatase [Haemophilus influenzae 3655], gi\|14498... GPH_HAEI8 - Phosphoglycolate phosphatase OS=Haemophilus influenzae (strain 86-028NP) GN=NTHI0697 PE=3 SV=1	8.0E-41	[1..237]	[1..224]
gi\|29144292, gi\|... - gi\|29144292\|ref\|NP_807634.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica serov... gi\|213865259 - gi\|213865259\|ref\|ZP_03387378.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica se... gi\|214000218 - gi\|214000218\|ref\|ZP_03410953.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica se... gi\|213426748 - gi\|213426748\|ref\|ZP_03359498.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica se... gi\|213648701 - gi\|213648701\|ref\|ZP_03378754.1\| phosphoglycolate phosphatase [Salmonella enterica subsp. enterica se...	1.0E-40	[1..237]	[1..239]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLSRVRAVF FDLDNTLIDT AGASRRGMLE VIKLLQSKYH YKEEAEIICD KVQVKLSKEC  60
   61 FHPYNTCITD LRTSHWEEAI QETKGGAANR KLAEECYFLW KSTRLQHMTL AEDVKAMLTE 120
  121 LRKEVRLLLL TNGDRQTQRE KIEACACQSY FDAVVVGGEQ REEKPAPSIF YYCCNLLGVQ 180
  181 PGDCVMVGDT LETDIQGGLN AGLKATVWIN KNGIVPLKSS PVPHYMVSSV LELPALLQSI 240
  241 DCKVSMST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.69897
Match:	2gfhA
Description:	No description for 2gfhA was found.

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.77831325452536	bayes_pls_golite062009
catalytic activity	1.55296860681783	bayes_pls_golite062009
N-acylneuraminate-9-phosphatase activity	0.971134270518015	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.0103445825744194	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: