YRC Public Data Repository - Protein Structure Prediction

Protein:	SRP72
Organism:	Saccharomyces cerevisiae
Length:	640 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRP72.

Description	E-value	Query Range	Subject Range
gi\|33640682, gi\|... - gi\|33862569\|ref\|NP_894129.1\| TPR repeat-containing protein [Prochlorococcus marinus str. MIT 9313], ...	9.0E-50	[1..595]	[498..1025]
gi\|151942591 - gi\|151942591\|gb\|EDN60937.1\| signal recognition particle component [Saccharomyces cerevisiae YJM789] SRP72 - Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functio... SRP72_YEAST - Signal recognition particle subunit SRP72 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G... gi\|190407753 - gi\|190407753\|gb\|EDV11018.1\| hypothetical protein SCRG_02289 [Saccharomyces cerevisiae RM11-1a]	2.0E-48	[1..629]	[1..629]
gi\|114594637 - gi\|114594637\|ref\|XP_001139671.1\| PREDICTED: signal recognition particle 72kDa isoform 4 [Pan troglod... gi\|182887899 - gi\|182887899\|gb\|AAI60164.1\| Signal recognition particle 72kDa [synthetic construct] SRP72 - signal recognition particle 72kDa	3.0E-45	[5..638]	[10..629]
SRP72_CANLF - Signal recognition particle subunit SRP72 OS=Canis lupus familiaris GN=SRP72 PE=1 SV=3	5.0E-44	[5..638]	[10..629]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...	8.0E-43	[5..534]	[10..492]
gi\|5052534 - gi\|5052534\|gb\|AAD38597.1\|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]	1.0E-42	[9..507]	[53..503]
gi\|13775066 - gi\|13775066\|gb\|AAK39123.1\|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]	1.0E-42	[9..534]	[24..502]

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Predicted Domain #1

Region A:
Residues: [1-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKDNLTNLL SQLNIQLSQD EHSQVEQTCV KLLDSGCENP ADVFRRCLVA VIQQDKYQKA  60
   61 LHYLKKFKHI DDKYGRKFAL EKLYIFYKLN MPDEFNTLYT AIITDDLDTV LKKDIESLRG 120
  121 ILHVRAQYCY KNGLYQEAFK IYQHLASHNE KDQDSQIELS CNERVPLSVA TELMNRSPLV 180
  181 TPMDESSYDL LFNESFIMAS VGKYDKAIEL LEKALQGATN EGYQNDINTI KLQLSFVLQM 240
  241 VGKTAQSKEI LKGLLQELKA DSPFSLICQN NLNAFVDFSK YNTNFNLLLR ELNVEKLNTF 300
  301 NLQTF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.0
Match:	1fchA_
Description:	Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [306-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THEQWSNIQR NVLFLRLFNN VKIHSQESLL SRTFDKYSKL VDNVTLESYK TQAKKLYHHT  60
   61 TKTILSGTDG STIGILLLTI QLLIIEKEWE NAIRIGELFL NESWKSSFEK FNDSQAIVCY 120
  121 ILFELYKIKG RNNSKSVLLK KLGSVRVQLS GKIQENIPFW KHVGFELLSM GNAKESKALL 180
  181 REISNF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [492-640]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKGDADVLVD RVVSSDSLDI AQGIDLVRDI DIDKLIQLGV KPLESSAKRS KNTAVSKVQK  60
   61 RKVLELKKKR KIKRLEKFLQ GRDTSKLPDP ERWLPLRDRS TYRPKKKQQG AKQTQGGAMN 120
  121 KKSEQALDIS KKGKPTVNKK PKNKKKGRK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits