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View Structure Prediction Details

Protein: SCM3
Organism: Saccharomyces cerevisiae
Length: 223 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCM3.

Description E-value Query
Range
Subject
Range
SCM3 - Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, re...
298.0 [0..1] [223..25]
gi|46107590, gi|... - gi|46107590|ref|XP_380854.1| hypothetical protein FG00678.1 [Gibberella zeae PH-1], gi|42544632|gb|E...
186.0 [0..56] [206..4]
gi|45187961, gi|... - gi|45187961|ref|NP_984184.1| ADR088Cp [Ashbya gossypii ATCC 10895], gi|44982745|gb|AAS52008.1| ADR08...
gi|44982745 - gi|44982745|gb|AAS52008.1| ADR088Cp [Ashbya gossypii ATCC 10895]
160.0 [0..19] [199..16]
gi|85116033 - gi|85116033|ref|XP_964982.1| hypothetical protein [Neurospora crassa OR74A]
gi|32420231, gi|... - gi|32420231|ref|XP_330559.1| hypothetical protein [Neurospora crassa], gi|28926781|gb|EAA35746.1| hy...
137.0 [0..55] [143..3]
gi|38567281 - gi|38567281|emb|CAE76571.1| hypothetical protein [Neurospora crassa]
136.0 [0..55] [143..3]
gi|49644448, gi|... - gi|50310585|ref|XP_455312.1| unnamed protein product [Kluyveromyces lactis], gi|49644448|emb|CAG9802...
gi|49644448 - gi|49644448|emb|CAG98020.1| KLLA0F05115p [Kluyveromyces lactis]
115.0 [0..1] [194..2]
gi|49526726 - gi|49526726|emb|CAG60353.1| unnamed protein product [Candida glabrata]
gi|49526726, gi|... - gi|50289969|ref|XP_447416.1| hypothetical protein CAGL0I03850g [Candida glabrata CBS138], gi|4952672...
108.0 [0..15] [195..20]
gi|49087430, gi|... - gi|67522114|ref|XP_659118.1| hypothetical protein AN1514.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
98.0 [0..88] [151..23]
gi|46443549, gi|... - gi|68468614|ref|XP_721626.1| hypothetical protein CaO19.9237 [Candida albicans SC5314], gi|68468371|...
orf19.9237, orf1... - orf19.1668 CGDID:CAL0000074 Assembly 19, Contig19-10123 (136059, 137930) CDS, translated using codon...
94.0 [0..81] [153..62]
SPAPB1A10.02 - chromosome segregation protein
YK12_SCHPO - Uncharacterized protein PB1A10.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPB1A1...
92.0 [0..90] [149..36]

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Predicted Domain #1
Region A:
Residues: [1-71]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTNKKISKR RSLKNLHGAL KGLLKESGKK SESKIRKHSD CNPVHRVYPP NIEKRKTKKD  60
   61 DGISRPIAER N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.447 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.447 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.390 a.159.2 FF domain
View Download 0.371 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.371 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.353 a.64.1 Saposin
View Download 0.350 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.341 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.287 a.60.1 SAM/Pointed domain

Predicted Domain #2
Region A:
Residues: [72-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHVYIMSKEN HIIPKLTDDE VMERHKLADE NMRKVWSNII SKYESIEEQG DLVDLKTGEI  60
   61 VEDNGHIKTL TANNSTKDKR TKYTSVLRDI IDISDEEDGD KNDEYTLWAN DSEASDSEVD 120
  121 ADNDTEEEKD EKLIDADFKK YEAKLSKRIL RD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.270 N/A N/A a.2.5 Prefoldin
View Download 0.247 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.243 N/A N/A d.83.1 Bactericidal permeability-increasing protein, BPI
View Download 0.235 N/A N/A d.110.4 SNARE-like
View Download 0.232 N/A N/A a.91.1 Regulator of G-protein signalling, RGS


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle