YRC Public Data Repository - Protein Structure Prediction

Protein:	PRS4
Organism:	Saccharomyces cerevisiae
Length:	327 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRS4.

Description	E-value	Query Range	Subject Range
gi\|34192133 - gi\|34192133\|gb\|AAH30019.2\| PRPS2 protein [Homo sapiens]	7.0E-93	[9..327]	[27..346]
gi\|28422233 - gi\|28422233\|gb\|AAH44286.1\| Prps1 protein [Xenopus laevis]	2.0E-92	[10..327]	[8..326]
gi\|22295271, gi\|... - gi\|22299089\|ref\|NP_682336.1\| ribose-phosphate pyrophosphokinase [Thermosynechococcus elongatus BP-1]...	3.0E-92	[9..323]	[83..396]
KPRS1_ARATH - Ribose-phosphate pyrophosphokinase 1, chloroplastic OS=Arabidopsis thaliana GN=PRS1 PE=2 SV=2	6.0E-92	[8..322]	[87..402]
gi\|33303737 - gi\|33303737\|gb\|AAQ02382.1\| phosphoribosyl pyrophosphate synthetase 1 [synthetic construct]	6.0E-92	[11..326]	[1..317]
gi\|38511773, gi\|... - gi\|45361007\|ref\|NP_989140.1\| similar to phosphoribosyl pyrophosphate synthetase 1 [Xenopus (Silurana...	7.0E-92	[11..327]	[1..318]
PRPS1_MOUSE - Ribose-phosphate pyrophosphokinase 1 OS=Mus musculus GN=Prps1 PE=1 SV=3	7.0E-92	[11..327]	[1..318]

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Predicted Domain #1

Region A:
Residues: [1-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSESREDMA INSIKLLAGN SHPDLAEQIS KKLGIPLSKV GVYQYSNKET SVTIGESLRD  60
   61 EDVYIIQTGI GEQEINDFLM ELLILIHACQ IASARKITTV IPNFPYARQD KKDKSRAPIT 120
  121 AKLVANLLQT AGADHVITMD LHASQIQGFF HIPVDNLYAE PSVLNYIRAR KTDFDNAILV 180
  181 SPDAGGAKRV AALADKLDLN FALIHKERQK ANEVSKMVLV GDVTNKSCLL VDDMADTCGT 240
  241 LVKACDTLME HGAKEVIAIV THGIFSGSAR EKLRNSRLSR IVCTNTVPVD LDLPIADQID 300
  301 ISPTFAEAIR RLHNGESVSY LFTHAPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.0
Match:	1dkrA_
Description:	Phosphoribosylpyrophosphate synthetase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits