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View Structure Prediction Details

Protein: AOS1
Organism: Saccharomyces cerevisiae
Length: 347 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AOS1.

Description E-value Query
Range
Subject
Range
gi|23124399, gi|... - gi|23124399|ref|ZP_00106391.1| COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and...
2.0E-81 [2..325] [5..343]
gi|29606732, gi|... - gi|29829624|ref|NP_824258.1| molybdopterin biosynthesis-like protein MoeZ [Streptomyces avermitilis ...
8.0E-81 [7..325] [12..350]
gi|22296131, gi|... - gi|22299946|ref|NP_683193.1| hypothetical protein tlr2403 [Thermosynechococcus elongatus BP-1], gi|2...
1.0E-80 [2..325] [5..343]
gi|9714466, gi|2... - gi|9714466|emb|CAC01308.1| putative sulfurylase [Streptomyces coelicolor A3(2)], gi|21223547|ref|NP_...
1.0E-80 [7..314] [12..336]
gi|35830 - gi|35830|emb|CAA40296.1| ubiquitin activating enzyme E1 [Homo sapiens]
2.0E-80 [1..343] [41..434]
gi|60654051, gi|... - gi|60654051|gb|AAX29718.1| ubiquitin-activating enzyme E1 [synthetic construct], gi|30584341|gb|AAP3...
3.0E-80 [1..343] [41..434]
UBA1_RABIT - Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus cuniculus GN=UBA1 PE=1 SV=1
6.0E-80 [1..343] [41..434]
gi|17230398, gi|... - gi|17230398|ref|NP_486946.1| hypothetical protein all2906 [Nostoc sp. PCC 7120], gi|17132000|dbj|BAB...
gi|25313623 - pir||AC2169 molybdopterin biosynthesis protein [imported] - Nostoc sp. (strain PCC 7120)
7.0E-80 [2..325] [5..343]
RHC31_YEAST - DNA damage tolerance protein RHC31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AOS1 ...
gi|190408102 - gi|190408102|gb|EDV11367.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|207340216 - gi|207340216|gb|EDZ68636.1| YPR180Wp-like protein [Saccharomyces cerevisiae AWRI1631]
AOS1 - Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugatio...
9.0E-80 [1..347] [1..347]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMKVEKLSE DEIALYDRQI RLWGMTAQAN MRSAKVLLIN LGAIGSEITK SIVLSGIGHL  60
   61 TILDGHMVTE EDLGSQFFIG SEDVGQWKID ATKERIQDLN PRIELNFDKQ DLQEKDEEFF 120
  121 QQFDLVVATE MQIDEAIKIN TLTRKLNIPL YVAGSNGLFA YVFIDLIEFI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 283.67837
Match: 1ngvA_
Description: Amyloid beta precursor protein-binding protein 1, APPBP1

Predicted Domain #2
Region A:
Residues: [171-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDEKLQSVR PTTVGPISSN RSIIEVTTRK DEEDEKKTYE RIKTKNCYRP LNEVLSTATL  60
   61 KEKMTQRQLK RVTSILPLTL SLLQYGLNQK GKAISFEQMK RDAAVWCENL GVPATVVKDD 120
  121 YIQQFIKQKG IEFAPVAAII GGAVAQDVIN ILGKRLSPLN NFIVFDGITL DMPLFEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 283.67837
Match: 1ngvA_
Description: Amyloid beta precursor protein-binding protein 1, APPBP1

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle