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View Structure Prediction Details

Protein: YPR174C
Organism: Saccharomyces cerevisiae
Length: 221 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPR174C.

Description E-value Query
Range
Subject
Range
YPR174C - Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear...
YP174_YEAST - Nuclear envelope protein YPR174C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPR174C...
YPR174C_W303 - ORF Verified Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes t...
0.0 [1..221] [1..221]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIQEKTLGI RKERKLVVVP RERNHVRHAS QRTRSKNYKN ISKKRAQQHA FGFNIAKTLA  60
   61 KIQAFVWGSP ADEEEESVVP LSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.606 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.481 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.406 a.4.5 "Winged helix" DNA-binding domain
View Download 0.400 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.396 a.4.5 "Winged helix" DNA-binding domain
View Download 0.374 a.2.7 tRNA-binding arm
View Download 0.351 a.4.5 "Winged helix" DNA-binding domain
View Download 0.318 f.13.1 Family A G protein-coupled receptor-like
View Download 0.313 f.15.1 Small-conductance potassium channel
View Download 0.279 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.279 i.1.1 Ribosome and ribosomal fragments
View Download 0.272 a.47.2 t-snare proteins
View Download 0.269 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.245 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.239 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.233 a.1.1 Globin-like
View Download 0.230 d.226.1 GIY-YIG endonuclease
View Download 0.211 a.77.1 DEATH domain
View Download 0.203 a.47.2 t-snare proteins

Predicted Domain #2
Region A:
Residues: [84-221]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSQDCVPLQW QAKFAQLRQQ LHSTQKELQF VKEKCHLLQS VLDDANIDQR YLESRRDMKN  60
   61 IERDNLKPTE NLPPSPVRAV NPLVTSSPIH MSPLQSRQRP VSSLQPPKGP NFYAKYPKLP 120
  121 QTNILRESPT EDSVPHAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.719 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.240 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.233 N/A N/A a.47.2 t-snare proteins
View Download 0.221 N/A N/A a.25.1 Ferritin-like
View Download 0.208 N/A N/A a.26.1 4-helical cytokines
View Download 0.203 N/A N/A a.7.1 Spectrin repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle