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View Structure Prediction Details

Protein: PIN3
Organism: Saccharomyces cerevisiae
Length: 215 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIN3.

Description E-value Query
Range
Subject
Range
PIN3 - Protein that induces appearance of [PIN+] prion when overproduced
PIN3_YEAST - [PSI+] inducibility protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PIN3 PE=1 ...
4.0E-42 [1..215] [1..215]
CSH3_SCHPO - Protein csh3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=csh3 PE=2 SV=1
SPBC119.05c - Wiskott-Aldrich syndrome homolog binding protein Lsb1
5.0E-30 [1..215] [83..296]
gi|17980553 - gi|17980553|gb|AAL50641.1|AF440203_1 Crk-based reporter [synthetic construct]
2.0E-29 [7..164] [323..478]
gi|3550240 - gi|3550240|gb|AAC36099.1| SH3 domain-containing adapter protein; CD2AP [Mus musculus]
7.0E-29 [6..194] [61..244]
gi|34365071 - gi|34365071|emb|CAE45892.1| hypothetical protein [Homo sapiens]
2.0E-28 [13..181] [318..491]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLINRSL TNIRTELDFL KGSNVISNDV YDQINKSLPA KWDPANAPRN ASPASLEYVE  60
   61 ALYQFDPQQD GDLGLKPGDK VQLLEKLSPE WYKGSCNGRT GIFPANYVKP AFSGSNGPSN 120
  121 LP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 161.503332
Match: 1griA_
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [123-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPQYKAQEL QQIPTQNSAA SSYQQQPFPP PSTNYYQQPQ QQPQQAPPPQ QQQQQQQHQS  60
   61 SHSHLKSFGS KLGNAAIFGA GASIGSDIVN NIF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle