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View Structure Prediction Details

Protein: SPN1
Organism: Saccharomyces cerevisiae
Length: 410 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPN1.

Description E-value Query
Range
Subject
Range
gi|7023152 - gi|7023152|dbj|BAA91858.1| unnamed protein product [Homo sapiens]
5.0E-78 [121..409] [1..281]
gi|12840232 - gi|12840232|dbj|BAB24793.1| unnamed protein product [Mus musculus]
7.0E-76 [137..409] [1..265]
gi|151942906 - gi|151942906|gb|EDN61252.1| suppresses postrecruitment functions gene number 1 [Saccharomyces cerevi...
SPN1 - Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcri...
gi|190408057 - gi|190408057|gb|EDV11322.1| transcription factor IWS1 [Saccharomyces cerevisiae RM11-1a]
gi|207340272 - gi|207340272|gb|EDZ68676.1| YPR133Cp-like protein [Saccharomyces cerevisiae AWRI1631]
IWS1_YEAST - Transcription factor SPN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPN1 PE=1 SV=1
3.0E-73 [1..410] [1..410]
gi|22832350, gi|... - gi|24642454|ref|NP_573115.1| CG9915-PA [Drosophila melanogaster], gi|22832350|gb|AAF48587.2| CG9915-...
8.0E-65 [69..409] [5..342]
gi|41581304, gi|... - gi|41581304|emb|CAE47953.1| hypothetical protein, conserved [Aspergillus fumigatus], gi|19309406|emb...
2.0E-62 [6..404] [2..415]
gi|2832628, gi|7... - pir||T05037 hypothetical protein F13C5.170 - Arabidopsis thaliana, gi|7268694|emb|CAB78902.1| putat...
2.0E-55 [20..407] [5..388]
CE05599 - status:Confirmed UniProt:Q19375 protein_id:CAA94590.1
2.0E-54 [5..409] [62..495]

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Predicted Domain #1
Region A:
Residues: [1-227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTADQEQPK VVEATPEDGT ASSQKSTINA ENENTKQNQS MEPQETSKGT SNDTKDPDNG  60
   61 EKNEEAAIDE NSNVEAAERK RKHISTDFSD DDLEKEEHND QSLQPTVENR ASKDRDSSAT 120
  121 PSSRQELEEK LDRILKKPKV RRTRRDEDDL EQYLDEKILR LKDEMNIAAQ LDIDTLNKRI 180
  181 ETGDTSLIAM QKVKLLPKVV SVLSKANLAD TILDNNLLQS VRIWLEP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [228-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPDGSLPSFE IQKSLFAALN DLPVKTEHLK ESGLGRVVIF YTKSKRVEAQ LAR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.437 a.4.1 Homeodomain-like
View Download 0.430 a.4.1 Homeodomain-like
View Download 0.395 a.4.1 Homeodomain-like
View Download 0.349 a.4.1 Homeodomain-like
View Download 0.329 a.4.1 Homeodomain-like
View Download 0.313 a.4.5 "Winged helix" DNA-binding domain
View Download 0.263 a.4.5 "Winged helix" DNA-binding domain
View Download 0.262 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.246 a.4.5 "Winged helix" DNA-binding domain
View Download 0.240 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.232 a.4.5 "Winged helix" DNA-binding domain
View Download 0.221 a.144.1 PABC (PABP) domain
View Download 0.221 a.50.1 Anaphylotoxins (complement system)

Predicted Domain #3
Region A:
Residues: [281-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAEKLIAEWT RPIIGASDNY RDKRIMQLEF DSEKLRKKSV MDSAKNRKKK SKSGEDPTSR  60
   61 GSSVQTLYEQ AAARRNRAAA PAQTTTDYKY APVSNLSAVP TNARAVGVGS TLNNSEMYKR 120
  121 LTSRLNKKHK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.223 0.209 RNA elongation from RNA polymerase II promoter a.1.1 Globin-like
View Download 0.234 0.043 RNA elongation from RNA polymerase II promoter a.118.8 TPR-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle