YRC Public Data Repository - Protein Structure Prediction

Protein:	CLB2
Organism:	Saccharomyces cerevisiae
Length:	491 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLB2.

Description	E-value	Query Range	Subject Range
gi\|151942896 - gi\|151942896\|gb\|EDN61242.1\| B-type cyclin [Saccharomyces cerevisiae YJM789] CG22_YEAST - G2/mitotic-specific cyclin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLB2 PE=1 S... gi\|190408046 - gi\|190408046\|gb\|EDV11311.1\| G2/mitotic-specific cyclin-2 [Saccharomyces cerevisiae RM11-1a] CLB2 - B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2...	0.0	[1..491]	[1..491]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[15..483]	[2..448]
CCNB1_MESAU - G2/mitotic-specific cyclin-B1 OS=Mesocricetus auratus GN=CCNB1 PE=2 SV=1	0.0	[77..486]	[2..426]
gi\|1835260 - gi\|1835260\|emb\|CAA99990.1\| mitotic cyclin [Sesbania rostrata]	0.0	[15..480]	[2..441]
gi\|254022 - gi\|254022\|gb\|AAB22970.1\| cyclin B1 [Mus sp.] CCNB1_MOUSE - G2/mitotic-specific cyclin-B1 OS=Mus musculus GN=Ccnb1 PE=1 SV=3	0.0	[77..486]	[2..427]
CCNB1_RAT - G2/mitotic-specific cyclin-B1 OS=Rattus norvegicus GN=Ccnb1 PE=2 SV=1	0.0	[77..486]	[2..420]
CCB12_ARATH - Cyclin-B1-2 OS=Arabidopsis thaliana GN=CYCB1-2 PE=1 SV=2	0.0	[15..479]	[5..434]
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1	0.0	[17..483]	[3..450]
CCNB1, CGB1 - chorionic gonadotropin, beta polypeptide 1, cyclin B1 gi\|123990181 - gi\|123990181\|gb\|ABM83901.1\| cyclin B1 [synthetic construct]	0.0	[77..486]	[2..430]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNPIENTEN SQNTSSSRFL RNVQRLALNN VTNTTFQKSN ANNPALTNFK STLNSVKKEG  60
   61 SRIPQFTRES VSRSTAAQEE KRTLKENGIQ LPKNNLLDDK ENQDPSSQQF GALTSIKEGR 120
  121 AELPANISLQ ESSSAKEIIQ HDPLKGVGSS TEVVHNSVEN EKLHPARSQL QVRNTESETD 180
  181 SGKKRPISTI VEQELPKKFK VCDENGKEEY EWEDLDAEDV NDP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [224-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FMVSEYVNDI FEYLHQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [361-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMNFLRRISK ADDYDIQSRT LAKFLLEISL VDFRFIGILP SLCAAAAMFM SRKMLGKGKW  60
   61 DGNLIHYSGG YTKEELAPVC HMIMDYLVSP IVHDEFHRKY QSRRFMKASI ISVQWALKVR 120
  121 KNGYDIMTLH E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	381.201249
Match:	1vin__
Description:	Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [240-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEVITLPKKE DLYQHRNIHQ NRDILVNWLV KIHNKFGLLP ETLYLAINIM DRFLGKELVQ  60
   61 LDKLQLVGTS CLFIASKYEE VYSPSIKHFA SETDGACTED EIKEGEKFIL KTLKFNLNYP 120
  121 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	381.201249
Match:	1vin__
Description:	Cyclin A
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits