YRC Public Data Repository - Protein Structure Prediction

Protein:	PIS1
Organism:	Saccharomyces cerevisiae
Length:	220 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIS1.

Description	E-value	Query Range	Subject Range
PIS1 - Phosphatidylinositol synthase, required for biosynthesis of phosphatidylinositol, which is a precurs... PIS_YEAST - CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Saccharomyces cerevisiae (strain ATCC 2045...	6.0E-34	[1..220]	[1..220]
PIS1_ARATH - CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1 OS=Arabidopsis thaliana GN=PIS1 PE=1 SV=2	1.0E-27	[3..215]	[2..226]
gi\|21745398 - gi\|21745398\|gb\|AAM77369.1\|AF521301_1 phosphatidylinositol synthase [Brassica napus]	4.0E-27	[3..215]	[2..226]
gi\|32403216, gi\|... - gi\|32403216\|ref\|XP_322221.1\| hypothetical protein [Neurospora crassa], gi\|28917240\|gb\|EAA26952.1\| hy... gi\|85078561 - gi\|85078561\|ref\|XP_956188.1\| hypothetical protein [Neurospora crassa OR74A]	2.0E-26	[10..205]	[114..309]
gi\|22027475 - gi\|22027475\|ref\|NP_665695.1\| CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform 2 [Homo ...	9.0E-26	[25..217]	[47..244]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNSTPEKV TAEHVLWYIP NKIGYVRVIT AALSFFVMKN HPTAFTWLYS TSCLLDALDG  60
   61 TMARKYNQVS SLGAVLDMVT DRSSTAGLMC FLCVQYPQWC VFFQLMLGLD ITSHYMHMYA 120
  121 SLSAGKTSHK SVGEGESRLL HLYYTRRDVL FTICAFNELF YAGLYLQLFS NSATFGKWTT 180
  181 IISFPGYVFK QTANVVQLKR AALILADNDA KNANEKNKTY

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	31.920819
Match:	PF01066
Description:	CDP-alcohol phosphatidyltransferase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits