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View Structure Prediction Details

Protein: RPN7
Organism: Saccharomyces cerevisiae
Length: 429 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN7.

Description E-value Query
Range
Subject
Range
RPN7 - Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae reg...
gi|151942884 - gi|151942884|gb|EDN61230.1| proteasome regulatory particle subunit [Saccharomyces cerevisiae YJM789]
gi|190408035 - gi|190408035|gb|EDV11300.1| 26S proteasome regulatory subunit RPN7 [Saccharomyces cerevisiae RM11-1a...
RPN7_YEAST - 26S proteasome regulatory subunit RPN7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R...
3.0E-74 [1..429] [1..429]
PSMD6_MOUSE - 26S proteasome non-ATPase regulatory subunit 6 OS=Mus musculus GN=Psmd6 PE=1 SV=1
6.0E-74 [12..423] [5..389]
gi|208965390 - gi|208965390|dbj|BAG72709.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [synthetic c...
ENSPTRT00000028219 - null
PSMD6 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
6.0E-74 [12..423] [5..389]
gi|27694784, gi|... - gi|27694784|gb|AAH43825.1| P44s10-prov protein [Xenopus laevis], gi|147904380|ref|NP_001080462.1| hy...
4.0E-73 [12..423] [5..389]
gi|29436940, gi|... - gi|41053583|ref|NP_956585.1| proteasome, 26S, non-ATPase regulatory subunit 6 [Danio rerio], gi|2943...
1.0E-69 [12..423] [5..386]
Rpn7-PA - The gene Rpn7 is referred to in FlyBase by the symbol Dmel\Rpn7 (CG5378, FBgn0028688). It is a prote...
gi|220956106 - gi|220956106|gb|ACL90596.1| Rpn7-PA [synthetic construct]
gi|194200351, gi... - gi|195572882|ref|XP_002104424.1| GD18456 [Drosophila simulans], gi|194200351|gb|EDX13927.1| GD18456 ...
6.0E-68 [12..422] [5..388]
PSMD6_ARATH - 26S proteasome non-ATPase regulatory subunit 6 homolog OS=Arabidopsis thaliana GN=RPN7 PE=1 SV=1
2.0E-66 [21..423] [10..387]
gi|125548775 - gi|125548775|gb|EAY94597.1| hypothetical protein OsI_16374 [Oryza sativa Indica Group]
PSMD6_ORYSJ - 26S proteasome non-ATPase regulatory subunit 6 OS=Oryza sativa subsp. japonica GN=RPN7 PE=2 SV=1
PSMD6_ORYSA, PSD... - 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory particle non-ATPase subuni...
2.0E-66 [21..423] [12..389]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-65 [21..423] [10..406]
gi|85085957 - gi|85085957|ref|XP_957611.1| hypothetical protein NCU03972 [Neurospora crassa OR74A]
gi|32405356, gi|... - gi|32405356|ref|XP_323291.1| hypothetical protein [Neurospora crassa], gi|28918704|gb|EAA28375.1| hy...
3.0E-65 [15..428] [4..491]

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Predicted Domain #1
Region A:
Residues: [1-90]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDVEEKSQE VEYVDPTVNR VPNYEVSEKA FLLTQSKVSI EQRKEAAEFV LAKIKEEEMA  60
   61 PYYKYLCEEY LVNNGQSDLE HDEKSDSLNE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.557 0.181 structural molecule activity a.118.1 ARM repeat
View Download 0.481 0.015 ubiquitin-dependent protein catabolic process a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.470 0.014 ubiquitin-dependent protein catabolic process a.74.1 Cyclin-like
View Download 0.520 0.002 ubiquitin-dependent protein catabolic process a.118.11 Cytochrome c oxidase subunit E
View Download 0.557 N/A N/A a.118.1 ARM repeat
View Download 0.520 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.481 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.470 N/A N/A a.74.1 Cyclin-like
View Download 0.428 N/A N/A a.74.1 Cyclin-like
View Download 0.428 N/A N/A a.118.8 TPR-like
View Download 0.413 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.396 N/A N/A a.74.1 Cyclin-like
View Download 0.373 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.362 N/A N/A a.118.8 TPR-like
View Download 0.351 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.346 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.332 N/A N/A d.211.1 Ankyrin repeat
View Download 0.317 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.306 N/A N/A a.29.4 RecG, N-terminal domain
View Download 0.303 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.301 N/A N/A a.26.1 4-helical cytokines
View Download 0.297 N/A N/A a.118.8 TPR-like
View Download 0.293 N/A N/A a.74.1 Cyclin-like
View Download 0.277 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.270 N/A N/A a.50.1 Anaphylotoxins (complement system)
View Download 0.236 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.232 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.230 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.213 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.208 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.206 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.206 N/A N/A a.77.1 DEATH domain

Predicted Domain #2
Region A:
Residues: [91-271]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WIKFDQELYN ELCKKNESKI KELNEKIQKL EEDDEGELEQ AQAWINLGEY YAQIGDKDNA  60
   61 EKTLGKSLSK AISTGAKIDV MLTIARLGFF YNDQLYVKEK LEAVNSMIEK GGDWERRNRY 120
  121 KTYYGIHCLA VRNFKEAAKL LVDSLATFTS IELTSYESIA TYASVTGLFT LERTDLKSKV 180
  181 I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1na0A_
Description: Designed protein cTPR3
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [272-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSPELLSLIS TTAALQSISS LTISLYASDY ASYFPYLLET YANVLIPCKY LNRHADFFVR  60
   61 EMRRKVYAQL LESYKTLSLK SMASAFGVSV AFLDNDLGKF IPNKQLNCVI DRVNGIVETN 120
  121 RPDNKNAQYH LLVKQGDGLL TKLQKYGAAV RLTGSDRV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [319-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKYLNRHADF FVREMRRKVY AQLLESYKTL SLKSMASAFG VSVAFLDNDL GKFIPNKQLN  60
   61 CVIDRVNGIV ETNRPDNKNA QYHLLVKQGD GLLTKLQKYG AAVRLTGSDR V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.045757
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle