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View Structure Prediction Details

Protein: GRS2
Organism: Saccharomyces cerevisiae
Length: 618 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRS2.

Description E-value Query
Range
Subject
Range
SYG_MOUSE - Glycine--tRNA ligase OS=Mus musculus GN=Gars PE=1 SV=1
0.0 [2..617] [104..719]
gi|12652637 - gi|12652637|gb|AAH00065.1| GARS protein [Homo sapiens]
0.0 [2..617] [114..729]
Aats-gly-PB, FBp... - The gene Glycyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-gly (CG6778, FBgn0...
0.0 [2..617] [146..761]
GRS2 - Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for ...
gi|190408014 - gi|190408014|gb|EDV11279.1| glycyl-tRNA synthetase 2 [Saccharomyces cerevisiae RM11-1a]
gi|151942862 - gi|151942862|gb|EDN61208.1| glycyl-tRNA synthase [Saccharomyces cerevisiae YJM789]
SYG2_YEAST - Glycine--tRNA ligase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRS2 PE=1 SV=1
0.0 [1..618] [1..618]
gi|15292923 - gi|15292923|gb|AAK92832.1| putative glycyl tRNA synthetase [Arabidopsis thaliana]
0.0 [5..612] [113..720]

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Predicted Domain #1
Region A:
Residues: [1-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLMSNSERD KLESTLRRRF FYTPSFEIYG GVSGLFDLGP PGCQLQNNLI RLWREHFIME  60
   61 ENMLQVDGPM LTPYDVLKTS GHVDKFTDWM CRNPKTGEYY RADHLIEQTL KKRLLDKDVN 120
  121 PQDMKNMEKI LTTIDGFSGP ELNLVMQEYN INDPVTNDVL DALTSFNLMF ETKIGASGQL 180
  181 KAFLRPETAQ GQFLNFNKLL EINQGKIPFA SASIGKSFRN EISPRSGLLR VREFLMAEIE 240
  241 HFVDPLNKSH AKFNEVLNEE IPLLSRRLQE SGEVQLPVKM TIGEAVNSGM VENETLGYFM 300
  301 ARVHQFLLNI GINKDKFRFR QHLKNEMAHY ATDCWDGEIL TSYGWIECVG CADRAAFDLT 360
  361 VHSKKTGRSL TVKQKLDTPK ERTEWVVEVN KKFFGSKFKQ KAKLIESVLS KFSQDELIRR 420
  421 HEELEKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 445.228787
Match: 1atiA_
Description: Glycyl-tRNA synthetase (GlyRS), C-terminal domain; Glycyl-tRNA synthetase (GlyRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [428-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEFTCQVNGQ IVKLDSSLVT IKMKTTLQHI REYIPNVIEP SFGLGRIIYC IFDHCFQVRV  60
   61 DSESRGFFSF PLQIAPIKVF VTTISNNDGF PAILKRISQA LRKREIYFKI DDSNTSIGKK 120
  121 YA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 445.228787
Match: 1atiA_
Description: Glycyl-tRNA synthetase (GlyRS), C-terminal domain; Glycyl-tRNA synthetase (GlyRS)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [550-618]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNDELGTPFG ITIDFETIKD QTVTLRERNS MRQVRGTITD VISTIDKMLH NPDESDWDKS  60
   61 TFGLSPVKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.218487
Match: 1nj8A_
Description: Prolyl-tRNA synthetase (ProRS) domain; C-terminal domain of ProRS; Prolyl-tRNA synthetase (ProRS)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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