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View Structure Prediction Details

Protein: MED1
Organism: Saccharomyces cerevisiae
Length: 566 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED1.

Description E-value Query
Range
Subject
Range
MED1_YEAST - Mediator of RNA polymerase II transcription subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 20450...
MED1 - Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ...
gi|207340352 - gi|207340352|gb|EDZ68729.1| YPR070Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408006 - gi|190408006|gb|EDV11271.1| essential for transcriptional regulation [Saccharomyces cerevisiae RM11-...
0.0 [1..566] [1..566]

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Predicted Domain #1
Region A:
Residues: [1-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEGDSYVET LDSMIELFKD YKPGSITLEN ITRLCQTLGL ESFTEELSNE LSRLSTASKI  60
   61 IVIDVDYNKK QDRIQDVKLV LASNFDNFDY FNQRDGEHEK SNILLNSLTK YPDLKAFHNN 120
  121 LKFLYLLDAY SHIESDSTSH NNGSSDKSLD SSNASFNNQG KLDLFKYFTE LSHYIRQCFQ 180
  181 DNCCDFKVRT NLNDKFGIYI LTQGINGKEV PLAKIYLEEN KSDSQYRFYE YIYSQETKSW 240
  241 INESAENFSN GISLVMEIVA NAKESNYTDL IWFPEDFISP ELIIDKVTCS SNSSSSPPII 300
  301 DLFSNNNYNS RIQLMNDFTT KLINIKKFDI SNDNLDLISE ILKWVQWSRI VLQNVFKLVS 360
  361 TPSSNSNSSE LEPDYQAPFS TSTKDKNSST SNTEPIPRSN RHGSVVEASR RRRSSTNKSK 420
  421 RPSITEAMML KEEGLQQFNL HEILSEPAIE EENGDSIKEH STTMDGANDL GFTASVSNQE 480
  481 NAGTDIVMED HGVLQGTSQN YGTATADDAD IEMKDVSSKP SKPESSVLQL IVSEDHIILD 540
  541 TISECNLYDD VKCWSKFIEK FQDIVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle