YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: TIF5
Organism: Saccharomyces cerevisiae
Length: 405 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIF5.

Description E-value Query
Range
Subject
Range
IF5_YEAST - Eukaryotic translation initiation factor 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
gi|151942829 - gi|151942829|gb|EDN61175.1| translation initiation factor eIF5 [Saccharomyces cerevisiae YJM789]
gi|190407984 - gi|190407984|gb|EDV11249.1| eukaryotic translation initiation factor 5 [Saccharomyces cerevisiae RM1...
TIF5 - Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to m...
0.0 [1..392] [1..392]
IF5_RAT - Eukaryotic translation initiation factor 5 OS=Rattus norvegicus GN=Eif5 PE=1 SV=1
0.0 [1..395] [1..383]
gi|147900740, gi... - gi|27469870|gb|AAH41737.1| Eif5-prov protein [Xenopus laevis], gi|147900740|ref|NP_001080311.1| euka...
0.0 [1..395] [1..381]
gi|1229140 - gi|1229140|gb|AAC50572.1| translation initiation factor 5
0.0 [1..395] [1..385]
eIF5-PF, eIF5-PE... - The gene eIF5 is referred to in FlyBase by the symbol Dmel\eIF5 (CG9177, FBgn0030719). It is a prote...
gi|220953394, gi... - gi|220953394|gb|ACL89240.1| eIF5-PA [synthetic construct], gi|220943194|gb|ACL84140.1| eIF5-PA [synt...
0.0 [2..395] [3..408]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..395] [1..385]
gi|56207822, gi|... - gi|56207822|emb|CAI21349.1| novel protein (zgc:77026) [Danio rerio], gi|46403257|gb|AAS92648.1| euka...
0.0 [1..393] [1..376]
SPAC2F7.05c - translation initiation factor eIF5
IF5_SCHPO - Probable eukaryotic translation initiation factor 5 OS=Schizosaccharomyces pombe (strain 972 / ATCC ...
1.0E-94 [2..392] [3..374]

Back

Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSINICRDNH DPFYRYKMPP IQAKVEGRGN GIKTAVLNVA DISHALNRPA PYIVKYFGFE  60
   61 LGAQTSISVD KDRYLVNGVH EPAKLQDVLD GFINK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.154902
Match: 1k8bA_
Description: Zinc-binding domain of translation initiation factor 2 beta
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [96-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVLCGSCKNP ETEIIITKDN DLVRDCKACG KRTPMDLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1k81A_
Description: Zinc-binding domain of translation initiation factor 2 beta
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [134-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKLSSFILKN PPDSVSGSKK KKKAATASAN VRGGGLSISD IAQGKSQNAP SDGTGSSTPQ  60
   61 HHDEDEDELS RQIKAAASTL EDIEVKDDEW AVDMSEEAIR ARAKELEVNS ELTQLDEYGE 120
  121 WILEQAGEDK ENLPSDVELY KKAAELDV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.240 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.260 N/A N/A b.82.2 Clavaminate synthase-like
View Download 0.232 N/A N/A a.29.2 Bromodomain
View Download 0.336 N/A N/A a.149.1 RNase III endonuclease catalytic domain
View Download 0.229 N/A N/A a.118.8 TPR-like
View Download 0.218 N/A N/A d.2.1 Lysozyme-like
View Download 0.213 N/A N/A a.75.1 Ribosomal protein S7

Predicted Domain #4
Region A:
Residues: [282-405]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNDPKIGCVL AQCLFDEDIV NEIAEHNAFF TKILVTPEYE KNFMGGIERF LGLEHKDLIP  60
   61 LLPKILVQLY NNDIISEEEI MRFGTKSSKK FVPKEVSKKV RRAAKPFITW LETAESDDDE 120
  121 EDDE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 36.119186
Match: PF02020
Description: eIF4-gamma/eIF5/eIF2-epsilon

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle