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View Structure Prediction Details

Protein: NTO1
Organism: Saccharomyces cerevisiae
Length: 748 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTO1.

Description E-value Query
Range
Subject
Range
NTO1 - Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finge...
NTO1_YEAST - NuA3 HAT complex component NTO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTO1 PE=...
0.0 [1..748] [1..748]
gi|30794210, gi|... - gi|30794210|ref|NP_084454.1| bromodomain and PHD finger containing, 1 [Mus musculus], gi|28277047|gb...
0.0 [43..688] [72..711]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [43..688] [72..712]
gi|168275726 - gi|168275726|dbj|BAG10583.1| peregrin [synthetic construct]
BRPF1 - bromodomain and PHD finger containing, 1
0.0 [43..688] [72..712]
gi|41056011, gi|... - gi|41056011|ref|NP_957310.1| bromodomain containing 1 [Danio rerio], gi|27881884|gb|AAH44418.1| Brom...
0.0 [40..689] [83..759]

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Predicted Domain #1
Region A:
Residues: [1-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRGSLDDGP KLREEKHFQD FYPDLNADTL LPFIVPLVET KDNSTDTDSD DISNRNNREI  60
   61 GSVKSVQTKE LIFKGRVTTE PLVLKKNEVE FQKCKITTNE LKGKKNPYCV RFNESFISRY 120
  121 YHINKVRNRK SYKQQQKEFD GVEAPYFTKF SSKEAPNITI STSTKSAIQK FASISPNLVN 180
  181 FKPQYDMDEQ DELYLHYLNK RYFKDQMSHE IFEILMTTLE TEWFHIEKHI PSTNSLIARH 240
  241 NILRDCKNYE LYGSDDG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [258-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGLSMDQACA VCLGTDSDNL NTIVFCDGCD IAVHQECYGI IFIPEGKWLC RRCMISKNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.045757
Match: 1f62A_
Description: Williams-Beuren syndrome transcription factor, WSTF
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [317-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FATCLMCPSH TGAFKQTDTG SWVHNICALW LPELYFSNLH YMEPIEGVQN VSVSRWKLNC  60
   61 YICKKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [383-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGACIQCFQR NCFTAYHVTC ARRAGLYMSK GKCTIQELAS NQFSQKYSVE SFCHKHAPRG  60
   61 WQTSIEGINK ARKYFSLLST LQTETPQHNE ANDRTNSKFN KTIWKTPNQT PVAPHVFAEI 120
  121 LQKVVDFFGL ANPPAGAFDI CKYWSMKREL TGGTPLTACF ENNSLGSLTE EQVQTRIDFA 180
  181 NDQLEDLYRL KELTTLVKKR TQASNSLSRS RKKVFDIVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [602-748]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPQKYLLKIN VLDIFIKSEQ FKALERLVTE PKLLVILEKC KHCDFDTVQI FKEEIMHFFE  60
   61 VLETLPGASR ILQTVSSKAK EQVTNLIGLI EHVDIKKLLS RDFIINDDKI EERPWSGPVI 120
  121 MEEEGLSDAE ELSAGEHRML KLILNSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.39794
Match: 1jm4B_
Description: P300/CAF histone acetyltransferase bromodomain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle